Zilpaterol is a synthetic β₂-adrenergic agonist associated primarily with veterinary and animal-health applications. The compound is identified by CAS No. 119520-05-7, molecular formula C₁₄H₁₉N₃O₂, and molecular weight 261.32 g/mol. It is also known by the development identifier RU-42173. These chemical identity details are independently listed by PubChem and LGC Standards.
Zilpaterol is structurally related to the β-adrenergic agonist class and has been used in veterinary applications involving cattle. LGC Standards describes Zilpaterol as a β-adrenergic agonist and growth promotant, while FDA documentation identifies zilpaterol hydrochloride as the active ingredient in the veterinary product Zilmax.
Zilpaterol has the molecular formula C₁₄H₁₉N₃O₂ and molecular weight 261.32 g/mol. Its accurate mass is approximately 261.1477, as reported by LGC Standards. PubChem provides the same molecular formula and molecular weight and identifies the compound by CAS No. 119520-05-7.
The compound contains defined stereocenters, and its chemical identity can be confirmed using appropriate analytical techniques such as chromatographic and spectrometric methods. LGC Standards provides the corresponding SMILES and InChI identifiers for analytical reference purposes.
Zilpaterol is primarily relevant to veterinary pharmaceutical and animal-health research, rather than human pharmaceutical applications. Its pharmacological activity is associated with β₂-adrenergic receptor agonism. LGC Standards categorizes the material as an API/reference material and reports purity of >95% by HPLC for its listed analytical material.
For organizations involved in veterinary pharmaceutical research, analytical testing and animal-health product development, Zilpaterol may be evaluated according to the required identity, purity, impurity profile and regulatory documentation.
Zilpaterol should be distinguished from Zilpaterol Hydrochloride, which is a different chemical form.
Zilpaterol base:
Zilpaterol Hydrochloride:
PubChem independently confirms the identity and molecular weight of Zilpaterol Hydrochloride.
There is also a separate Zilpaterol Hydrochloride Monohydrate form with CAS No. 186046-04-8 and molecular formula C₁₄H₂₂ClN₃O₃, so these forms should not be combined on the same product page or treated as interchangeable materials.
Quality evaluation of Zilpaterol should begin with confirmed chemical identity and chromatographic purity. LGC Standards lists Zilpaterol as an API reference material with >95% HPLC purity, together with chemical identifiers including molecular formula, molecular weight, accurate mass, SMILES and InChI.
For a commercial or pharmaceutical-grade material, the applicable specification should be established using the manufacturer's validated analytical methods and batch-specific Certificate of Analysis. Parameters such as related substances, residual solvents, water content, elemental impurities and other quality attributes should not be assigned generic numerical limits without supporting product documentation.
This distinction is particularly important for Zilpaterol because publicly available analytical-reference material specifications should not automatically be treated as universal commercial API release specifications.
Swapnroop Drugs and Pharmaceuticals' website describes the company as an API manufacturer in India, bulk API supplier and pharmaceutical raw material exporter, with WHO-GMP certification and global supply activities. The website states that the company serves customers across more than 25 countries and offers APIs, excipients and pharmaceutical raw materials.
For Zilpaterol-related requirements, buyers and veterinary pharmaceutical organizations should specify the required chemical form, grade, purity, quantity and regulatory documentation before procurement.
The distinction between Zilpaterol base, Zilpaterol Hydrochloride and Zilpaterol Hydrochloride Monohydrate is especially important when preparing a purchase specification or requesting a Certificate of Analysis.
Zilpaterol is associated with veterinary and animal-health applications. FDA documentation for Zilmax identifies zilpaterol hydrochloride as the active ingredient and specifies its use in finishing cattle feed. The same FDA labeling states that the product is not for use in humans.
Relevant areas include:
The exact permitted use, formulation and regulatory status depend on the applicable jurisdiction and product authorization.
Organizations sourcing Zilpaterol should evaluate the material against the appropriate specification and intended use. Documentation may include:
LGC Standards lists its Zilpaterol material with a storage temperature of -20°C and shipping temperature of blue ice. These conditions relate to that particular reference material and should not automatically be treated as the storage specification for every Zilpaterol product.
Zilpaterol is a specialized compound requiring clear identification of its chemical form and intended veterinary application. When evaluating Zilpaterol API requirements, purchasers should provide the desired specification, quantity, grade and documentation requirements so that the appropriate material can be evaluated.
For bulk API and veterinary pharmaceutical raw-material enquiries, technical requirements should be confirmed before commercial supply. This helps ensure that the supplied material corresponds to the requested Zilpaterol form, purity and analytical specification.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | >98.5% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 20 ppm |
| Total Impurities | NMT 0.5% |
| Melting Point | 157–158°C |