Swapnroop Drugs & Pharmaceuticals is a manufacturer and supplier of Vericiguat API for pharmaceutical formulation, development, research and regulated pharmaceutical manufacturing applications.
Vericiguat is a synthetic small-molecule pharmaceutical active ingredient and a soluble guanylate cyclase (sGC) stimulator. It is used in pharmaceutical formulations for the treatment of selected patients with symptomatic chronic heart failure following a worsening heart-failure event.
Vericiguat is identified by CAS No. 1350653-20-1, with molecular formula C₁₉H₁₆F₂N₈O₂ and molecular weight 426.39 g/mol. Regulatory assessment describes vericiguat as a white to yellowish powder and confirms its structure using spectroscopic and analytical techniques including IR, Raman spectroscopy, NMR, mass spectrometry and elemental analysis.
Vericiguat is a synthetic sGC stimulator that enhances the nitric oxide–sGC–cGMP signaling pathway. It is commercially used as an active pharmaceutical ingredient in oral tablets.
Regulatory product information identifies Vericiguat as the active ingredient in 2.5 mg, 5 mg and 10 mg film-coated tablets.
As a pharmaceutical API, Vericiguat requires appropriate control of identity, assay, impurities, water content and other applicable physical and chemical characteristics. Regulatory assessment confirms that the drug-substance specification includes appearance, identity, impurities, water content, particle size and assay.
Vericiguat API is primarily used for pharmaceutical formulations intended for cardiovascular applications.
Key applications include:
Vericiguat stimulates soluble guanylate cyclase and increases intracellular cyclic guanosine monophosphate (cGMP), supporting its pharmacological action in cardiovascular disease.
Vericiguat is a chemically defined small-molecule API requiring appropriate analytical control throughout pharmaceutical manufacturing.
Relevant quality attributes may include:
Regulatory assessment confirms that the drug-substance specification includes appearance, identity, impurities, water content, particle size and assay.
Swapnroop Drugs & Pharmaceuticals provides Vericiguat API manufacturing and supply support for pharmaceutical companies, formulation manufacturers and qualified customers involved in cardiovascular pharmaceutical development.
As a Vericiguat API manufacturer and supplier in India, Swapnroop supports customers requiring controlled API quality, analytical documentation and pharmaceutical supply.
Vericiguat API can support:
Vericiguat API should be stored in suitable tightly closed pharmaceutical-grade containers under controlled environmental conditions.
The material should be protected from excessive moisture, heat, light and other unsuitable environmental exposure. Storage conditions should follow the applicable product specification and validated stability requirements.
Typical pharmaceutical documentation may include:
Quality control of Vericiguat API should include validated analytical procedures suitable for the drug substance.
Important quality attributes include identity, assay, related substances, water content and particle size. Regulatory assessment confirms that the drug substance specification incorporates these controls.
Because Vericiguat is a synthetic small molecule, conventional pharmaceutical API testing can include chromatographic purity and assay methods together with physical and chemical characterization.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical manufacturers and qualified customers seeking Vericiguat API for formulation, development and regulated pharmaceutical manufacturing applications.
Our approach focuses on:
Swapnroop supports customers looking for Vericiguat API Manufacturer and Supplier in India for cardiovascular pharmaceutical applications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0–102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.10% |
| Heavy Metals | NMT 20 ppm |
| Individual Impurity | NMT 0.50% |
| Total Impurities | NMT 1.00% |
| Water Content | NMT 1.0% |