Swapnroop Drugs & Pharmaceuticals is a manufacturer and supplier of Verapamil Hydrochloride API for pharmaceutical formulation, development, research and regulated pharmaceutical manufacturing applications.
Verapamil Hydrochloride is the hydrochloride salt of verapamil and belongs to the phenylalkylamine class of calcium channel blockers. It acts as a calcium ion influx inhibitor and is used as an active pharmaceutical ingredient in cardiovascular pharmaceutical formulations. Verapamil Hydrochloride affects calcium ion movement through slow channels in cardiac and vascular smooth muscle cells, contributing to its effects on cardiac conduction, heart rate and vascular tone.
Verapamil Hydrochloride is identified by CAS No. 152-11-4, with molecular formula C27H38N2O4·HCl and molecular weight approximately 491.08 g/mol. It is described as a white or practically white crystalline powder and is soluble in water.
Verapamil Hydrochloride is a synthetic small-molecule pharmaceutical compound classified as a calcium channel blocker. It inhibits the transmembrane influx of calcium ions into myocardial and vascular smooth muscle cells.
The compound is commercially important as an API for pharmaceutical formulations used in cardiovascular applications. Verapamil Hydrochloride is available in pharmaceutical dosage forms including immediate-release oral tablets, extended-release oral formulations and injectable preparations.
The chemical identity, molecular formula and molecular weight are consistent with current pharmaceutical labeling and chemical reference information.
Verapamil Hydrochloride API is primarily used in pharmaceutical development and manufacturing of cardiovascular medicines.
Key applications include:
Verapamil Hydrochloride produces pharmacological effects by reducing calcium ion influx through slow channels in myocardial and vascular smooth muscle cells. This activity contributes to reduced vascular resistance, effects on cardiac conduction and modulation of cardiac contractility.
Verapamil Hydrochloride requires appropriate controls for identity, assay, related substances, residual solvents, water content and other applicable quality attributes as part of pharmaceutical API quality management.
The active pharmaceutical ingredient should be manufactured and tested using validated analytical procedures appropriate for the drug substance and the intended regulatory market.
Quality evaluation may include analytical testing for identity, purity, assay and relevant impurities. Depending on the applicable specification, additional testing may be performed for residual solvents, water content, elemental impurities and other critical quality attributes.
For pharmaceutical manufacturing, acceptance criteria should be established according to the applicable pharmacopoeial requirements, approved specifications, validated analytical methods and customer requirements.
Swapnroop Drugs & Pharmaceuticals provides Verapamil Hydrochloride API manufacturing and supply support for pharmaceutical companies, formulation developers and qualified customers involved in cardiovascular pharmaceutical development and manufacturing.
As a Verapamil Hydrochloride API manufacturer and supplier in India, Swapnroop supports requirements involving:
Verapamil Hydrochloride API should be stored in suitable tightly closed pharmaceutical-grade containers under controlled environmental conditions.
The material should be protected from excessive moisture, heat, light and unsuitable environmental exposure. Storage conditions should follow the applicable product specification, safety documentation and validated stability requirements.
For commercial pharmaceutical API handling, exact storage conditions should be established according to the manufacturer's stability data, packaging configuration and applicable regulatory documentation.
Typical pharmaceutical documentation may include:
Documentation requirements may vary according to the customer's intended market, regulatory requirements and qualification process.
Quality control for Verapamil Hydrochloride API may include analytical evaluation of identity, assay, related substances, residual solvents, water content and other applicable pharmaceutical quality attributes.
Verapamil Hydrochloride is a defined hydrochloride salt with the molecular formula C27H38N2O4·HCl and molecular weight of approximately 491.08 g/mol. It is described as a white or practically white crystalline powder and is soluble in water.
Appropriate analytical methods should be used to confirm the identity and purity of the active pharmaceutical ingredient. Chromatographic, spectroscopic and other validated analytical techniques may be used according to the applicable specification and regulatory requirements.
Because Verapamil Hydrochloride is used in different pharmaceutical dosage forms, including oral and injectable products, API quality requirements should be established according to the intended application and applicable regulatory market.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical manufacturers and qualified customers seeking Verapamil Hydrochloride API for formulation, development and regulated pharmaceutical manufacturing applications.
Our approach focuses on:
Swapnroop supports customers looking for Verapamil Hydrochloride API Manufacturer and Supplier in India for cardiovascular and pharmaceutical applications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |