Swapnroop Drugs & Pharmaceuticals is a manufacturer and supplier of Venlafaxine Hydrochloride API for pharmaceutical formulation, development, research and regulated pharmaceutical manufacturing applications.
Venlafaxine Hydrochloride, commonly known as Venlafaxine HCl, is a synthetic small-molecule pharmaceutical active ingredient belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used in pharmaceutical formulations for the management of depressive disorders and other approved psychiatric indications.
Venlafaxine Hydrochloride is identified by CAS No. 99300-78-4, with molecular formula C₁₇H₂₈ClNO₂ and molecular weight approximately 313.86 g/mol.
Venlafaxine Hydrochloride is the hydrochloride salt of venlafaxine. It is a racemic synthetic compound containing a cyclohexanol structure, dimethylaminoethyl group and methoxyphenyl group.
Venlafaxine primarily inhibits the neuronal reuptake of serotonin and norepinephrine, while its effect on dopamine reuptake is comparatively weaker. Its pharmacological activity is associated with increased availability of these neurotransmitters in the central nervous system.
The API is used in the manufacture of pharmaceutical dosage forms, particularly oral formulations. Its hydrochloride salt form provides the pharmaceutical substance used in commercial formulations.
Venlafaxine Hydrochloride API is primarily used for pharmaceutical formulations in the CNS therapeutic area.
Applications include:
Venlafaxine is pharmacologically associated with inhibition of serotonin and norepinephrine reuptake, supporting its use as an SNRI pharmaceutical ingredient.
Venlafaxine Hydrochloride is a well-characterized synthetic pharmaceutical API with established pharmacopoeial quality requirements.
Quality evaluation can include:
The Indian Pharmacopoeia monograph specifies loss on drying NMT 0.5% and sulphated ash NMT 0.1%. It also describes the material as freely soluble in water and methanol, soluble in anhydrous ethanol and slightly soluble or practically insoluble in acetone.
Swapnroop Drugs & Pharmaceuticals provides Venlafaxine Hydrochloride API manufacturing and supply support for pharmaceutical companies, formulation manufacturers and qualified customers.
As a Venlafaxine Hydrochloride API manufacturer and supplier in India, Swapnroop supports customers requiring pharmaceutical-grade API with controlled specifications, analytical documentation and reliable supply.
Venlafaxine HCl can support requirements involving:
Venlafaxine Hydrochloride should be stored in well-closed pharmaceutical-grade containers under controlled environmental conditions.
The material should be protected from excessive moisture, unsuitable heat and direct environmental exposure. Pharmacopoeial storage guidance specifies preservation in well-closed containers at controlled room temperature.
Typical pharmaceutical documentation may include:
Documentation availability may depend on the product grade, intended market and customer requirements.
Venlafaxine Hydrochloride has established pharmacopoeial specifications for assay and impurities.
The current USP-derived specification gives an assay range of 98.0–102.0% on the dried basis, loss on drying NMT 0.5%, residue on ignition NMT 0.1%, and heavy metals NMT 20 ppm.
The organic impurity specification includes limits for descyclohexanol venlafaxine, didesmethyl venlafaxine, venlafaxine related compound A, deoxy venlafaxine and unspecified individual impurities. Total impurities are controlled at NMT 0.50% under the USP-derived specification.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical manufacturers and qualified customers seeking Venlafaxine Hydrochloride API for formulation, development and manufacturing applications.
Our approach focuses on:
Swapnroop supports customers looking for Venlafaxine Hydrochloride API Manufacturer and Supplier in India.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0–102.0% on dried basis |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 20 ppm |
| Individual Impurity | NMT 0.10% |
| Total Impurities | NMT 0.50% |