Swapnroop Drugs & Pharmaceuticals is a manufacturer and supplier of Vasopressin API for pharmaceutical formulation, peptide drug development, research and regulated pharmaceutical manufacturing applications.
Vasopressin, also known as Arginine Vasopressin (AVP) or Argipressin, is a synthetic cyclic nonapeptide and an important pharmaceutical active ingredient. It is structurally related to the naturally occurring antidiuretic hormone and produces its pharmacological effects primarily through interaction with vasopressin receptors.
Vasopressin is used in pharmaceutical products requiring vasopressor and antidiuretic activity, including formulations used in critical-care and other regulated medical applications.
The peptide consists of nine amino-acid residues and contains an intramolecular disulfide bond between the cysteine residues. The pharmaceutical active form is arginine vasopressin, with the molecular formula C₄₆H₆₅N₁₅O₁₂S₂ and molecular weight approximately 1084.23 g/mol. USP and FDA-linked substance information identify arginine vasopressin as a recognized pharmaceutical substance.
Vasopressin is a synthetic peptide API rather than a conventional small-molecule pharmaceutical ingredient. Its structure is based on a cyclic nonapeptide containing a disulfide bridge between Cys¹ and Cys⁶.
The peptide sequence is:
Cys–Tyr–Phe–Gln–Asn–Cys–Pro–Arg–Gly-NH₂
The arginine residue at position 8 gives the peptide its designation as arginine vasopressin. The cyclic structure and disulfide bond are important structural characteristics associated with its biological activity.
USP currently includes Vasopressin among peptide therapies supported by official USP-NF monographs and reference materials.
The 113-79-1 CAS identity is used for arginine vasopressin by the USP reference standard and PubChem. Some commercial databases also use 11000-17-2 for records labelled Vasopressin, so the exact substance identity should be tied to the intended pharmaceutical grade and analytical specification.
Vasopressin API is used for pharmaceutical development and manufacturing of products associated with vasopressor and antidiuretic activity.
Potential pharmaceutical applications include:
Vasopressin produces vasoconstrictive effects through vasopressin receptor activity and contributes to water-retaining effects through its antidiuretic mechanism.
As a peptide API, Vasopressin requires analytical and quality controls appropriate for peptide drug substances. These may include identity, peptide purity, related substances, water content, residual solvents, inorganic residues and biological potency, depending on the applicable specification.
USP resources describe peptide quality assessment using techniques including chromatographic purity, structural characterization, water determination and other peptide-specific analytical approaches.
For Vasopressin, a generic small-molecule assay format such as 98.0–102.0% HPLC should not automatically be applied. Pharmaceutical specifications should be based on the applicable USP-NF monograph, validated analytical method and approved product/manufacturer specification.
Swapnroop Drugs & Pharmaceuticals provides Vasopressin API manufacturing and supply support for pharmaceutical companies, formulation developers and qualified customers involved in peptide pharmaceutical development and manufacturing.
As a Vasopressin API manufacturer and supplier in India, Swapnroop focuses on controlled API quality, appropriate analytical documentation, specification-based manufacturing and reliable pharmaceutical supply.
Vasopressin API can support:
Vasopressin API should be stored in suitable pharmaceutical-grade, tightly closed containers under controlled conditions appropriate for peptide drug substances.
The material should be protected from excessive moisture, heat, light and other unsuitable environmental conditions. Storage conditions should follow the applicable product specification and validated stability data.
For peptide APIs, the recommended storage condition can depend on the physical presentation, packaging configuration and stability characteristics of the specific material.
Typical pharmaceutical documentation may include:
Documentation requirements may vary according to the intended pharmaceutical application, destination market and customer requirements.
Vasopressin is a peptide API and therefore requires quality assessment methods appropriate to its molecular structure and biological activity.
Relevant quality attributes may include:
USP identifies Vasopressin as a peptide API supported by official standards and emphasizes peptide-specific quality assessment approaches.
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical manufacturers and qualified customers seeking Vasopressin API for formulation, development and manufacturing applications.
Our approach focuses on:
Swapnroop supports pharmaceutical customers looking for Vasopressin API Manufacturer and Supplier in India for regulated pharmaceutical applications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Melting Point | 150°C – 154°C |