Trifarotene API Manufacturer and Supplier in India

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Trifarotene API Manufacturer and Supplier in India

Swapnroop Drugs & Pharmaceuticals is a pharmaceutical API manufacturer and supplier of Trifarotene, a selective retinoic acid receptor gamma (RAR-γ) agonist used primarily in topical pharmaceutical formulations for the treatment of acne vulgaris.

Trifarotene is identified by CAS No. 895542-09-3, molecular formula C29H33NO4, and molecular weight 459.59 g/mol. It is a synthetic, non-steroidal retinoid and is the active pharmaceutical ingredient in topical Trifarotene products. FDA chemistry documentation identifies it as a terphenyl acid derivative and a retinoid.

Trifarotene API Overview

Trifarotene is a highly selective RAR-γ agonist belonging to a newer generation of topical retinoids. Its selective receptor activity supports its use in dermatological formulations for acne vulgaris.

The FDA-approved topical product AKLIEF contains trifarotene at 0.005% concentration. FDA chemistry documentation describes trifarotene as a new molecular entity and provides its chemical identity as C29H33NO4 with molecular weight 459.59 g/mol.

Chemical and Pharmaceutical Profile

  • Product Name: Trifarotene
  • Synonyms: CD5789, RAR-γ Agonist, Trifarotene
  • CAS Number: 895542-09-3
  • UNII: 0J8RN2W0HK
  • Molecular Formula: C29H33NO4
  • Molecular Weight: 459.59 g/mol
  • Chemical Class: Retinoid / Terphenyl Carboxylic Acid Derivative
  • Pharmacological Class: Selective RAR-γ Agonist
  • Therapeutic Category: Dermatology
  • API Type: Synthetic Small-Molecule API
  • Physical Form: Solid
  • Appearance: White to off-white/cream solid
  • Melting Point: Approximately 245°C
  • pKa: Approximately 5.69

PubChem identifies CAS 895542-09-3, C29H33NO4, molecular weight 459.6 g/mol, UNII 0J8RN2W0HK and a reported melting point of approximately 245°C.

Pharmaceutical Applications

Trifarotene API is used in pharmaceutical applications involving:

  • Acne vulgaris treatment
  • Topical retinoid formulations
  • Dermatological pharmaceutical development
  • Selective RAR-γ agonist formulations
  • Retinoid research and development
  • Pharmaceutical formulation development

Trifarotene API Manufacturer and Supplier

Swapnroop Drugs & Pharmaceuticals supports pharmaceutical customers requiring Trifarotene API for topical dermatological formulation development and pharmaceutical manufacturing.

As a Trifarotene API manufacturer and supplier in India, Swapnroop focuses on chemical identity, assay, related-substance control, residual solvents, moisture and other applicable quality attributes according to the relevant pharmaceutical specification.

Packaging and Storage

Trifarotene should be maintained in suitable pharmaceutical packaging under controlled conditions and protected from environmental exposure according to the validated API stability and storage specification.

Because Trifarotene is a potent retinoid intended for pharmaceutical use, appropriate handling and contamination-control procedures should be followed during manufacturing and packaging.

Documentation

Typical pharmaceutical documentation may include:

  • Certificate of Analysis (CoA)
  • Product Specification
  • Batch Analytical Report
  • Safety Data Sheet (SDS)
  • Identification Data
  • Assay Report
  • Related-Substance / Impurity Profile
  • Residual Solvent Data
  • Water / Moisture Data
  • Stability Documentation
  • Manufacturing Documentation
  • Regulatory Documentation, where applicable

Why Choose Swapnroop for Trifarotene API?

Swapnroop Drugs & Pharmaceuticals provides pharmaceutical customers with reliable Trifarotene API supply for dermatological and topical retinoid applications, with emphasis on consistent chemical quality, appropriate impurity control and pharmaceutical documentation.

Detailed Specifications

Parameter Specification
Appearance white to off-white crystalline powder
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