Trientine Hydrochloride API Manufacturer and Supplier in India

Swapnroop Pharma · WHO-GMP Certified · +91 87670 62101

Trientine Hydrochloride API Manufacturer and Supplier in India

Swapnroop Drugs & Pharmaceuticals is a pharmaceutical API manufacturer and supplier of Trientine Hydrochloride, also known as Trientine Dihydrochloride or Triethylenetetramine Dihydrochloride. It is a synthetic copper-chelating agent used primarily in pharmaceutical applications related to Wilson's disease, particularly where treatment with penicillamine is unsuitable or insufficient.

Trientine Hydrochloride is identified by CAS No. 38260-01-4, molecular formula C6H20Cl2N4, and molecular weight 219.15 g/mol. FDA/GSRS and PubChem identify this substance as the dihydrochloride salt of triethylenetetramine.

Trientine Hydrochloride API Overview

Trientine is a polyamine copper chelator. Following administration, it binds excess copper and facilitates its elimination from the body. Trientine Hydrochloride has been used as the active substance in pharmaceutical products for the treatment of Wilson's disease, an inherited disorder associated with abnormal copper accumulation.

The FDA records the historical approval of Trientine HCl (Syprine) for patients with Wilson's disease who are intolerant of, or inadequately responsive to, penicillamine.

Chemical and Pharmaceutical Profile

  • Product Name: Trientine Hydrochloride
  • Synonyms: Trientine Dihydrochloride, Triethylenetetramine Dihydrochloride, Triethylene Tetramine Dihydrochloride
  • CAS Number: 38260-01-4
  • UNII: HC3NX54582
  • Molecular Formula: C6H20Cl2N4
  • Molecular Weight: 219.15 g/mol
  • Parent Compound: Triethylenetetramine
  • Parent CAS: 112-24-3
  • Chemical Class: Polyamine / Amine Hydrochloride
  • Pharmacological Class: Copper Chelating Agent
  • Therapeutic Category: Wilson's Disease / Copper Metabolism
  • API Type: Synthetic Small-Molecule API

PubChem identifies CAS 38260-01-4, formula C6H20Cl2N4 and molecular weight 219.15 g/mol for Trientine Hydrochloride.

Pharmaceutical Applications

Trientine Hydrochloride API is used for pharmaceutical applications involving:

  • Wilson's disease
  • Copper chelation therapy
  • Treatment of copper accumulation disorders
  • Pharmaceutical development of copper-chelating agents
  • Formulation development for oral chelation therapy

Trientine Hydrochloride API Manufacturer and Supplier

Swapnroop Drugs & Pharmaceuticals supports pharmaceutical companies requiring Trientine Hydrochloride API for formulation development and pharmaceutical manufacturing.

As a Trientine Hydrochloride API manufacturer and supplier in India, Swapnroop focuses on controlled chemical identity, assay, salt form, related substances, moisture and other applicable quality attributes according to the relevant pharmaceutical specification.

Packaging and Storage

Trientine Hydrochloride should be handled in suitable pharmaceutical packaging under controlled storage conditions. Packaging should protect the API from contamination and environmental exposure and should comply with the applicable validated product specification.

Documentation

Typical pharmaceutical documentation may include:

  • Certificate of Analysis (CoA)
  • Product Specification
  • Batch Analytical Report
  • Safety Data Sheet (SDS)
  • Identification Data
  • Assay Report
  • Related-Substance Profile
  • Residual Solvent Data
  • Water / Moisture Data
  • Stability Documentation
  • Manufacturing Documentation
  • Regulatory Documentation, where applicable

Why Choose Swapnroop for Trientine Hydrochloride API?

Swapnroop Drugs & Pharmaceuticals provides pharmaceutical customers with reliable Trientine Hydrochloride API supply for copper-chelation and Wilson's disease pharmaceutical applications, with emphasis on product identity, consistency and appropriate pharmaceutical documentation.

Detailed Specifications

Parameter Specification
Appearance white to off-white crystalline powder
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