Swapnroop Drugs & Pharmaceuticals is a pharmaceutical API manufacturer and supplier of Trichlormethiazide, a synthetic thiazide diuretic used in pharmaceutical formulations for the management of hypertension and edema.
Trichlormethiazide is identified by CAS No. 133-67-5, molecular formula C8H8Cl3N3O4S2, and molecular weight 380.66 g/mol. It is a chlorinated benzothiadiazine derivative with diuretic and antihypertensive activity.
Trichlormethiazide belongs to the thiazide diuretic class. It promotes renal excretion of sodium and water and is used therapeutically for hypertension and edema.
The substance is described in official pharmacopoeial material as a white powder. It is freely soluble in N,N-dimethylformamide and acetone, slightly soluble in acetonitrile and ethanol, and practically insoluble in water.
FDA's GSRS substance record confirms the molecular formula, molecular weight and racemic stereochemical description.
Trichlormethiazide API is used in pharmaceutical applications involving:
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical customers requiring Trichlormethiazide API for formulation development and commercial pharmaceutical manufacturing.
As a Trichlormethiazide API manufacturer and supplier in India, Swapnroop focuses on controlled chemical identity, assay, moisture, inorganic impurities, related substances and residual-solvent requirements according to the applicable pharmaceutical specification.
Trichlormethiazide should be stored in well-closed pharmaceutical containers under controlled conditions and protected from excessive moisture and contamination. The Japanese Pharmacopoeia specifies well-closed containers for the drug substance.
Typical pharmaceutical documentation may include:
Swapnroop Drugs & Pharmaceuticals provides pharmaceutical customers with reliable Trichlormethiazide API supply for thiazide diuretic and cardiovascular pharmaceutical applications, with emphasis on consistent quality and appropriate analytical documentation.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 20 ppm |
| Individual Impurity | NMT 2.5% |