Swapnroop Drugs & Pharmaceuticals is a pharmaceutical API manufacturer and supplier of Tretinoin, also known as all-trans-Retinoic Acid (ATRA) or Retinoic Acid. Tretinoin is a synthetic retinoid and vitamin A metabolite used in pharmaceutical applications, including dermatological formulations and treatment regimens for acute promyelocytic leukemia (APL).
Tretinoin is identified by CAS No. 302-79-4, molecular formula C20H28O2, and molecular weight 300.44 g/mol. USP identifies Tretinoin as retinoic acid/all-trans-retinoic acid.
Tretinoin is the all-trans isomer of retinoic acid and belongs to the retinoid class of pharmaceutical compounds. It acts through nuclear retinoic acid receptors and influences cellular differentiation and proliferation.
Tretinoin is used in pharmaceutical products for acute promyelocytic leukemia and in topical dermatological preparations for conditions including acne vulgaris. FDA chemistry documentation identifies Tretinoin as a drug substance used in approved topical products and describes it as sparingly soluble in water and sensitive to oxygen and light.
PubChem identifies Tretinoin as all-trans-retinoic acid with CAS 302-79-4, C20H28O2 and molecular weight 300.4 g/mol. Reported physical data describe it as a yellow to light-orange crystalline powder with a melting range around 180–184°C and very low water solubility.
Tretinoin API is used in pharmaceutical applications involving:
Swapnroop Drugs & Pharmaceuticals provides Tretinoin API for pharmaceutical formulation and manufacturing applications.
As a Tretinoin API manufacturer and supplier in India, Swapnroop supports pharmaceutical customers requiring controlled-quality Tretinoin with appropriate identification, assay, moisture, inorganic impurity and stereochemical/isomer-related quality controls according to the applicable specification.
Tretinoin is sensitive to light and oxygen. USP specifies preservation in tight containers, preferably under an inert atmosphere, with protection from light. Tretinoin should therefore be handled using suitable light-protective packaging and controlled storage conditions.
Typical pharmaceutical documentation may include:
Swapnroop Drugs & Pharmaceuticals supports pharmaceutical customers seeking reliable Tretinoin API supply for dermatological and oncology applications, with emphasis on product identity, purity, controlled handling and appropriate pharmaceutical documentation.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 97.0–103.0% on dried basis |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Melting Point | 180–184°C |