Swapnroop Drugs & Pharmaceuticals is a pharmaceutical Toremifene API manufacturer and supplier in India, providing pharmaceutical-grade active pharmaceutical ingredients for qualified pharmaceutical manufacturers, formulation companies, research organizations, and bulk procurement requirements.
Toremifene is a non-steroidal selective estrogen receptor modulator (SERM) belonging to the triphenylethylene class. It acts primarily as an estrogen receptor antagonist in breast tissue and has been used in the treatment of estrogen-receptor-positive or receptor-unknown metastatic breast cancer in postmenopausal women.
Toremifene is supplied as the Z-isomer (cis-toremifene) for pharmaceutical applications. Its CAS number is 89778-26-7, molecular formula is C₂₆H₂₈ClNO, and molecular weight is approximately 405.96 g/mol.
Toremifene is chemically identified as 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine. It is structurally related to tamoxifen and belongs to the triphenylethylene family of estrogen receptor modulators.
Toremifene has been characterized as a white to off-white crystalline powder. Its reported melting point is approximately 108–110°C for the free base.
Toremifene is a selective estrogen receptor modulator (SERM) used in oncology. Its antiestrogenic activity at breast-tissue estrogen receptors makes it useful in hormonal treatment of appropriate breast cancer patients.
Toremifene is particularly associated with treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor-positive or unknown tumors.
Swapnroop supports qualified pharmaceutical companies, formulation manufacturers, research organizations, and procurement teams requiring Toremifene API for pharmaceutical development and manufacturing applications.
The API can be supplied according to applicable pharmaceutical specifications and customer requirements, with appropriate quality and technical documentation subject to the applicable supply arrangement.
Toremifene API should be stored in a suitable pharmaceutical-grade, tightly closed container and protected from excessive environmental exposure. Historical pharmaceutical references indicate that Toremifene is sensitive to ultraviolet light, making appropriate light-protective packaging important.
Depending on the supply arrangement, documentation may include:
Swapnroop Drugs & Pharmaceuticals provides Toremifene API for qualified pharmaceutical, formulation, research, and bulk procurement requirements.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | NLT 98.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Heavy Metals | NMT 20 ppm |
| Melting Point | 108–110°C |