Tianeptine Sodium API is the sodium salt of Tianeptine, a tricyclic compound used as an antidepressant in certain markets. The pharmaceutical substance is chemically classified as a tricyclic antidepressant and is characterized by its sodium salt form. The commonly referenced API has CAS No. 30123-17-2, molecular formula C₂₁H₂₄ClN₂NaO₄S, and molecular weight 458.9 g/mol.
Tianeptine Sodium is described in the British Pharmacopoeia 2025 / Ph. Eur. 11.6 update with a content requirement of 99.0%–101.0% on the anhydrous substance. It is described as a white or yellowish, very hygroscopic powder and is freely soluble in water, methanol and methylene chloride.
Swapnroop Drugs & Pharmaceuticals focuses on quality-oriented Tianeptine Sodium API manufacturing in India, supporting authorized pharmaceutical customers with API quality, analytical testing and documentation requirements.
Tianeptine Sodium is the sodium salt of Tianeptine. It contains a tricyclic benzothiazepine-related structure with a heptanoic acid sodium salt functionality and sulfur dioxide group.
PubChem confirms the molecular formula, molecular weight and CAS number for Tianeptine Sodium.
Tianeptine Sodium is chemically identified as sodium 7-[[(11RS)-3-chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl]amino]heptanoate S,S-dioxide.
The sodium salt has a molecular weight of 458.9 g/mol. Its pharmaceutical properties differ from those of free Tianeptine, which has the formula C₂₁H₂₅ClN₂O₄S. Therefore, the free acid and sodium salt should not be combined into a single product specification.
Tianeptine has historically been described as a tricyclic antidepressant. Its pharmacological profile differs from that of conventional tricyclic antidepressants and selective serotonin reuptake inhibitors.
Tianeptine has been studied for effects involving serotonin neurotransmission and glutamatergic signaling. Its exact pharmacological profile depends on the biological and clinical context.
Tianeptine Sodium API is associated with pharmaceutical formulations developed for:
The regulatory status and permitted use of Tianeptine vary between countries, so commercial pharmaceutical use should follow the applicable local regulatory requirements.
Tianeptine Sodium API can be evaluated using appropriate pharmacopoeial and validated analytical procedures, including:
The BP monograph uses liquid chromatography for related substances and provides specific system-suitability requirements for the analytical procedure.
Tianeptine Sodium is described as very hygroscopic, therefore appropriate moisture-protective packaging is important. The BP monograph specifies storage in an airtight container.
Recommended packaging considerations include:
Depending on customer and regulatory requirements, documentation may include:
Swapnroop Drugs & Pharmaceuticals focuses on quality-oriented pharmaceutical API manufacturing for authorized pharmaceutical customers.
As a Tianeptine Sodium API Manufacturer in India, Swapnroop focuses on:
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 99.0% – 101.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Water Content | NMT 5.0% |