Thiocolchicoside IR Pellets Manufacturer India

Swapnroop Pharma · WHO-GMP Certified · +91 87670 62101

Thiocolchicoside IR Pellets (CAS No: 602-41-5) — Immediate Release Multiparticulates

Thiocolchicoside IR Pellets are immediate-release pharmaceutical pellets manufactured from Thiocolchicoside (C₂₇H₃₃NO₁₀S, MW ≈563.6), a GABA_A-receptor antagonist used as a muscle relaxant with analgesic effects. The drug substance is a yellow solid, soluble in water and in absolute ethanol, and insoluble in ether and acetone. Swapnroop Drugs and Pharmaceuticals manufactures Thiocolchicoside IR Pellets at its WHO-GMP certified Aurangabad, Maharashtra facility for pharmaceutical formulators in India and export markets.

Formulation Approach
Thiocolchicoside IR pellets are produced by drug-layering onto an inert core with minimal or no functional coating, to achieve rapid disintegration and dissolution for fast-onset muscle-relaxant/analgesic action.

Key Features

  • Immediate-release multiparticulate formulation
  • Drug substance is a characteristically yellow-colored solid (note this for appearance/CoA fields — do not describe as white)
  • Suitable for hard-gelatin capsule filling and multiparticulate tablet formulations
  • WHO-GMP manufactured with full batch documentation

Applications

  • Acute painful muscle contractures/spasm formulations
  • Musculoskeletal pain management, often as part of fixed-dose combinations with NSAIDs
  • Generic ANDA/CTD dossier programs

Why Choose Swapnroop for Thiocolchicoside IR Pellets?

  • WHO-GMP certified facility with drug-layering capability
  • Full CoA, MSDS, and DMF-grade documentation for regulated-market submissions

FAQs

  • What color should Thiocolchicoside pellets be? The drug substance itself is a yellow solid, so finished pellets are typically yellow to pale-yellow rather than white — confirm and correct the "Appearance" field for this product specifically.
  • Is Thiocolchicoside soluble in water? Yes — it is soluble in water and in 100% ethanol, and insoluble in ether and acetone.

Detailed Specifications

Parameter Specification
Appearance white to off-white crystalline powder
Identification IR & HPLC compliant
Assay (HPLC) 98.0% – 102.0%
Loss on Drying NMT 1.0%
Residue on Ignition NMT 0.5%
Heavy Metals NMT 20 ppm
Individual Impurity NMT 0.5%
Total Impurities NMT 1.0%
Water Content NMT 1.0%
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