Pharmaceutical-Grade Sucrose-Based Pellets for Pellet Layering, Coating and Multiparticulate Formulations
Sucrose-Based Pellets are pharmaceutical excipient starter pellets primarily composed of sucrose and starch. They provide a spherical, free-flowing core that can be used for layering, coating and development of multiparticulate oral dosage formulations. Pharmacopoeial Sugar Spheres contain 62.5% to 91.5% sucrose on a dried basis, with the remaining portion consisting chiefly of starch.
Sucrose-based pellet cores are used as a neutral substrate for the application of active ingredients, functional polymers and other formulation layers. Their approximately spherical geometry, controlled particle-size range and suitable surface characteristics support consistent coating and layering processes. Pharmaceutical literature identifies sugar spheres as established starter cores used in multiparticulate formulation development.
As a Sucrose-Based Pellets Manufacturer in India, Swapnroop provides pharmaceutical-grade pellet solutions intended for formulation development, coating, layering and capsule or other oral dosage applications. Product characteristics such as particle size, density, friability and surface properties can be controlled according to the applicable product specification.
Sucrose-Based Pellets can be used as starter or core pellets in pharmaceutical formulation processes, including:
Pharmacopoeial Sugar Spheres contain 62.5–91.5% sucrose, calculated on the dried basis, while the remainder consists chiefly of starch.
This composition distinguishes Sucrose-Based Pellets from purified sucrose powder. Therefore, the finished pellet should not automatically be assigned a 99–101% sucrose assay. The appropriate finished-product specification depends on the pellet composition and applicable standard.
Sucrose-Based Pellets can be supplied in suitable pharmaceutical packaging according to product requirements. Particle-size range, packaging quantity and other physical parameters should be confirmed against the applicable batch specification before commercial supply.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Individual Impurity | NMT 0.5% |
| Water Content | NMT 0.5% |