Sodium Pyrithione is a specialty cosmetic ingredient and antimicrobial compound historically associated with scalp-care, anti-dandruff and preservative applications. It is also known as 2-Mercaptopyridine N-Oxide Sodium Salt and Pyrithione Sodium. The primary CAS Number is 3811-73-2, with the molecular formula C₅H₄NNaOS and molecular weight 149.15 g/mol. PubChem identifies Sodium Pyrithione as the sodium salt of pyrithione and describes its antimicrobial and fungistatic properties.
Sodium Pyrithione has historically been associated with hair and scalp formulations, particularly products developed for dandruff-control applications. For businesses researching Sodium Pyrithione cosmetic ingredient manufacturer in India, the raw material should be evaluated according to its chemical identity, grade, purity, physical form, analytical specification and intended market.
Importantly, regulatory status varies by jurisdiction. Sodium Pyrithione is currently listed in Annex II, entry 369, of the EU Cosmetics Regulation as a prohibited substance in cosmetic products. Therefore, the page should distinguish technical raw-material information and historical cosmetic applications from current permission to use the substance in finished cosmetics.
Sodium Pyrithione is a sodium salt of pyrithione and is chemically described as sodium 1-oxidopyridine-2-thione. PubChem reports its molecular formula as C₅H₄NNaOS and molecular weight as 149.15 g/mol. CAS 3811-73-2 is the principal CAS identifier, while 15922-78-8 is also associated with Sodium Pyrithione records. The principal EC number is 223-296-5.
The material can occur in different commercial forms. Anhydrous Sodium Pyrithione is available as a crystalline powder or solid, while commercial aqueous products are also supplied at approximately 40% active content. TCI lists a 40% aqueous grade, while Thermo Fisher lists an anhydrous grade with an assay range of 97.5–102.5% by non-aqueous acid-base titration. These values are supplier-specific references and should not automatically be adopted as an SDP release specification.
Sodium Pyrithione has been associated with antimicrobial, anti-dandruff and preservative functionality in cosmetic and personal-care ingredient references. Its antimicrobial characteristics historically made it relevant to formulations where control of microorganisms on the scalp or in the product was an important formulation objective.
The ingredient's functional properties depend on the formulation environment and the form in which it is supplied. Factors such as concentration, pH, solubility, processing conditions and compatibility with other raw materials should be evaluated during product development.
Because Sodium Pyrithione is currently prohibited in EU cosmetics, manufacturers should not interpret historical anti-dandruff or preservative use as evidence of current authorization in the EU.
Historically, Sodium Pyrithione has been associated with hair-care and scalp-care formulations, particularly anti-dandruff shampoos and specialty personal-care products. Technical references also describe its antimicrobial activity against bacteria, fungi, yeasts and algae.
For technical B2B applications, Sodium Pyrithione may also be encountered in non-cosmetic antimicrobial uses, including industrial preservative systems. Commercial 40% aqueous grades are marketed for antimicrobial applications outside cosmetics as well.
When evaluating Sodium Pyrithione cosmetic ingredient in India, the intended finished-product market should be established before procurement. Regulatory permission, permitted concentration and product-category requirements must be checked for the destination country.
Sodium Pyrithione is highly water-compatible in suitable commercial forms. A 40% aqueous product is supplied as a liquid, while anhydrous Sodium Pyrithione is supplied as a solid. TCI describes the 40% aqueous material as approximately 3.3 mol/L, while industrial technical specifications commonly report an alkaline pH for aqueous grades.
Formulators should distinguish carefully between anhydrous Sodium Pyrithione and aqueous Sodium Pyrithione grades, because active content, physical form, water content and handling requirements differ. Compatibility with surfactants, conditioning agents, emulsifiers and other formulation ingredients should be established through formulation trials.
For commercial procurement, the analytical method must also be identified clearly. For example, Thermo Fisher specifies its anhydrous material by non-aqueous acid-base titration, while other commercial references provide HPLC purity values. An assay should therefore not be labelled Assay (HPLC) unless the actual SDP product is tested using a validated HPLC method.
Businesses searching for a Sodium Pyrithione cosmetic ingredient manufacturer in India should evaluate chemical identity, active content, physical form, analytical method, impurity profile, packaging, COA, SDS and batch traceability. A Sodium Pyrithione cosmetic ingredient supplier in India should provide product-specific technical documentation so buyers can determine whether the material matches their intended application.
For Sodium Pyrithione manufacturing in India and bulk ingredient supply, the commercial specification should clearly define whether the material is supplied as anhydrous solid or aqueous grade. Bulk buyers may also require specific active-content limits, packaging configuration and batch documentation.
Because Sodium Pyrithione is prohibited in EU cosmetics, the ingredient should be marketed carefully as a technical specialty material, with current destination-market regulatory verification before any finished-cosmetic application.
Swapnroop can position Sodium Pyrithione for B2B technical ingredient sourcing in India, with attention to product-specific identity, physical form, quality specifications and application requirements.
For businesses researching a Sodium Pyrithione cosmetic ingredient manufacturer and supplier in India, important considerations include the selected grade, active content, analytical method, technical documentation, packaging and bulk supply requirements. Final cosmetic use should always be evaluated against the current regulations of the intended destination market.
| Parameter | Specification |
|---|---|
| Appearance | White or colourless crystals / white powder |
| Assay (HPLC) | 97.5–102.5% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | Approximately 8.5–10.5 |
| Melting Point | 52–257°C |