Sodium Gluconate is the sodium salt of gluconic acid and is a multifunctional cosmetic ingredient used primarily for its chelating and formulation-supporting properties. It is identified by the INCI name SODIUM GLUCONATE and is also known as Sodium D-Gluconate or monosodium D-gluconate.
Sodium Gluconate is a highly water-compatible material and is generally supplied as a white to tan granular or fine crystalline powder. It is very soluble in water and only sparingly soluble in ethanol.
Its ability to interact with metal ions makes it particularly useful in cosmetic formulations where trace-metal control can be important for maintaining formulation stability and appearance. Sodium Gluconate can therefore be considered for skin-care, cleansing and other personal-care systems where a water-soluble chelating ingredient is required.
Sodium Gluconate has CAS Number 527-07-1 and EC Number 208-407-7. Its chemical name is Sodium D-Gluconate, with the molecular formula C₆H₁₁NaO₇ and molecular weight 218.14 g/mol. These identity details are confirmed by NIST, PubChem and USP.
Structurally, Sodium Gluconate is the sodium salt of D-gluconic acid and contains multiple hydroxyl groups. This polyhydroxylated structure contributes to its high water solubility and its ability to form complexes with certain metal ions.
The ingredient should be distinguished from Gluconolactone, which has CAS 90-80-2 and is the lactone form of gluconic acid. Sodium Gluconate is instead the sodium salt of the fully oxidized gluconic-acid structure.
Sodium Gluconate is principally relevant as a chelating cosmetic ingredient. Chelating ingredients bind certain metal ions that can otherwise participate in reactions affecting the stability, color or appearance of cosmetic formulations.
Its water solubility makes Sodium Gluconate convenient for aqueous formulation systems. It can therefore be considered when formulators need a water-compatible ingredient for systems where metal-ion management is part of the formulation strategy.
Sodium Gluconate can also contribute to the overall formulation environment through its ionic and water-soluble nature. Its actual functionality depends on concentration, formulation pH, the metal ions present and the other ingredients used in the finished product.
Sodium Gluconate can be considered for various personal-care and cosmetic formulations, including skin-care products, cleansing systems, lotions, creams, gels and other water-based formulations.
Its high water solubility allows it to be incorporated into aqueous phases. A USP-testing-grade material is reported as having a useful pH range of 6.5–7.5, while a commercial USP/FCC specification reports pH 6.5–7.5 for a 10% solution.
Sodium Gluconate is also used in non-cosmetic applications as a sequestrant and functional gluconate salt. Those applications demonstrate its chemical functionality but should not automatically be interpreted as cosmetic claims.
The quality specification for Sodium Gluconate should identify the assay basis, pH test concentration, impurities and elemental limits. USP defines Sodium Gluconate as containing 98.0–102.0% of C₆H₁₁NaO₇.
A USP/FCC product specification from Jungbunzlauer reports 99.0–101.0% assay, pH 6.5–7.5 at 10% solution, chloride NMT 50 mg/kg, sulfate NMT 100 mg/kg, lead below 2 mg/kg, heavy metals below 10 mg/kg, and reducing substances NMT 0.5%. These values are associated with that particular USP/FCC/EC specification and should not automatically be treated as a universal cosmetic specification.
The Assay (HPLC) field should not automatically contain 98–102% or 99–101%. The USP monograph establishes the assay range but the numerical value should only be entered under HPLC if the actual product is tested using a validated HPLC method. Where the applicable method is titrimetric or another analytical technique, the CMS should identify the correct method instead.
Sodium Gluconate is a useful water-soluble cosmetic ingredient for manufacturers seeking chelating functionality in personal-care formulations. Its combination of high water solubility and gluconate chemistry makes it relevant to formulations where trace-metal management and formulation stability are considerations.
For B2B cosmetic raw-material sourcing, the selected grade should clearly identify CAS number, molecular formula, assay method, pH test concentration, elemental impurities, reducing substances and physical characteristics.
As a Sodium Gluconate Cosmetic Ingredient Manufacturer in India, the focus is on controlled raw-material specifications, consistent quality characteristics and suitability for bulk cosmetic and personal-care formulation requirements.
| Parameter | Specification |
|---|---|
| Appearance | White or colourless crystals / white powder |
| Assay (HPLC) | 98.0–102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.2% |
| Individual Impurity | NMT 0.5% |
| Water Content | NMT 1.0% |
| Melting Point | Approximately 170–175°C |