sh-Polypeptide-15 is a recombinant human peptide associated with Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) and is used as a specialized cosmetic skin-conditioning ingredient. It is produced through recombinant biotechnology using fermentation in E. coli.
sh-Polypeptide-15 is suitable for selected advanced cosmetic formulations such as facial serums, creams, lotions, masks and other premium peptide-based skin-care products.
sh-Polypeptide-15 is a single-chain recombinant human peptide produced through fermentation in E. coli. The starting gene is synthesized to be identical to the human gene coding for Tissue Inhibitor of Metalloproteinases-2.
The ingredient contains a maximum of 220 amino acids and may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
Its primary cosmetic function is Skin Conditioning.
sh-Polypeptide-15 can be incorporated into cosmetic formulations where specialized recombinant peptide ingredients are required for skin-conditioning applications.
Common formulation formats include:
The concentration, carrier system and processing conditions should be selected according to the technical documentation for the specific commercial grade.
sh-Polypeptide-15 is used as a skin-conditioning ingredient in advanced skin-care formulations. Its association with TIMP-2 makes it a specialized peptide ingredient for premium cosmetic formulation development.
Potential applications include:
Formulators should consider:
sh-Polypeptide-15 can be incorporated into suitable cosmetic systems. Actual solubility depends on the commercial grade, concentration, carrier system and finished formulation.
As a recombinant peptide/protein-based cosmetic ingredient, unnecessary exposure to excessive heat should be avoided. Where appropriate, incorporation during the cooler stage of processing can help maintain peptide integrity.
The supplier's technical documentation should be followed for exact processing conditions.
The formulation pH should be selected according to the specific commercial grade and finished-product requirements. Compatibility and stability should be evaluated during formulation development.
Storage conditions are grade-specific. The supplier's TDS, SDS and COA should be followed for the exact storage temperature, packaging and shelf-life requirements.
sh-Polypeptide-15 can be considered for:
sh-Polypeptide-15 is a recombinant human peptide associated with Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) and used primarily as a skin-conditioning cosmetic ingredient.
The INCI name is sh-Polypeptide-15.
The CosIng record does not assign a CAS number to sh-Polypeptide-15. Therefore, N/A / Not Assigned is appropriate unless the specific commercial material has a CAS number documented in its supplier COA/TDS.
The CosIng reference is 86051.
The primary cosmetic function is Skin Conditioning.
sh-Polypeptide-15 is associated with Tissue Inhibitor of Metalloproteinases-2 (TIMP-2).
The ingredient description specifies a maximum of 220 amino acids.
Yes. It is described as a single-chain recombinant human peptide produced through fermentation in E. coli.
Yes. It can be considered for suitable peptide-based facial serum formulations.
Yes. It can be incorporated into suitable cosmetic creams and moisturizing formulations.
Storage requirements depend on the commercial grade. The supplier's TDS, SDS and COA should be followed for exact storage conditions.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |