sh-Polypeptide-1 is a recombinant or synthetic human peptide used as a cosmetic skin-conditioning ingredient. It is associated with Basic Fibroblast Growth Factor (bFGF/FGF2) and is produced through recombinant biotechnology. The ingredient is a specialized polypeptide used in advanced cosmetic formulations such as facial serums, creams, lotions and other premium skin-care products.
sh-Polypeptide-1 is listed under the INCI name SH-POLYPEPTIDE-1 and has a primary cosmetic function of Skin Conditioning.
sh-Polypeptide-1 is a single-chain synthetic human peptide produced through fermentation in E. coli. The starting gene is a synthesized copy of the human gene coding for Basic Fibroblast Growth Factor, which can be adapted for production in the host organism.
The CosIng description specifies a maximum of 288 amino acids and indicates that the peptide may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
sh-Polypeptide-1 can be incorporated into advanced cosmetic formulations where specialized peptide-based skin-conditioning ingredients are required.
Common formulation formats include:
The ingredient should be incorporated according to the technical specifications and recommended processing conditions of the selected commercial grade.
sh-Polypeptide-1 is used as a skin-conditioning ingredient in advanced skin-care formulations. Its specialized peptide structure makes it suitable for premium cosmetic products developed around peptide and growth-factor-inspired ingredient systems.
Potential applications include:
Formulators should consider:
sh-Polypeptide-1 can be incorporated into suitable water-based cosmetic systems. The actual solubility depends on the commercial grade, concentration, carrier system and finished formulation.
As a peptide/protein-based cosmetic ingredient, unnecessary exposure to high temperatures should be avoided. Where appropriate, the ingredient can be incorporated during the cooler stage of formulation processing according to the supplier's technical recommendations.
The formulation pH should be selected according to the specific commercial grade and finished-product requirements. Compatibility and stability should be evaluated during formulation development.
Storage conditions are grade-specific. The supplier's TDS, SDS and COA should be followed for the exact storage temperature, packaging and shelf-life requirements.
sh-Polypeptide-1 can be considered for:
sh-Polypeptide-1 is a specialized human peptide associated with Basic Fibroblast Growth Factor and used primarily as a skin-conditioning cosmetic ingredient.
The INCI name is sh-Polypeptide-1.
Some commercial and ingredient databases identify CAS 106096-93-9 with sh-Polypeptide-1. The current CosIng record itself does not list a CAS number, so the CAS should be confirmed against the actual supplier COA/TDS before final CMS publication.
The CosIng reference is 89445.
The primary listed cosmetic function is Skin Conditioning.
The CosIng description specifies a maximum of 288 amino acids.
Yes. It can be considered for suitable peptide-based facial serum formulations.
Yes. It can be incorporated into suitable cosmetic creams and moisturizing formulations.
sh-Polypeptide-1 is associated with Basic Fibroblast Growth Factor (bFGF/FGF2).
Storage requirements depend on the specific commercial grade. The supplier's TDS and COA should be followed for exact storage conditions.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |