sh-Oligopeptide-1 is a recombinant human peptide used as a cosmetic skin-conditioning ingredient. It is associated with human epidermal growth factor (EGF) and is produced through recombinant biotechnology using fermentation-based production systems. The ingredient is listed in the cosmetic ingredient nomenclature under the INCI name sh-Oligopeptide-1 and is primarily used in advanced skin-care formulations.
sh-Oligopeptide-1 is suitable for cosmetic formulations such as facial serums, creams, lotions, masks and other premium skin-care products where peptide-based skin-conditioning ingredients are required.
sh-Oligopeptide-1 is a single-chain recombinant human peptide produced through fermentation in E. coli. Its starting genetic sequence is designed based on the human gene associated with epidermal growth factor.
The ingredient contains a maximum of 53 amino acids and may contain disulfide bonds and/or sugar structures. In cosmetic applications, sh-Oligopeptide-1 is primarily classified for its skin-conditioning function.
It is commonly associated with recombinant human EGF and is used in advanced cosmetic formulations focused on skin-conditioning applications.
sh-Oligopeptide-1 can be incorporated into cosmetic formulations where peptide-based skin-conditioning ingredients are required. It is particularly suitable for advanced skin-care products designed around concentrated or premium cosmetic ingredient systems.
Common formulation formats include:
The ingredient should be incorporated according to the technical specifications and recommended processing conditions of the selected commercial grade.
sh-Oligopeptide-1 is used as a skin-conditioning ingredient in cosmetic skin-care formulations. Its recombinant peptide identity makes it suitable for formulations where specialized peptide ingredients are desired.
Potential skin-care applications include:
Formulators should consider the following parameters when working with sh-Oligopeptide-1:
sh-Oligopeptide-1 can be used in water-based cosmetic systems. Some commercial grades are reported as readily soluble in water. Actual solubility depends on the concentration, carrier system, formulation composition and specific commercial grade.
Because sh-Oligopeptide-1 is a peptide/protein ingredient, unnecessary exposure to high temperatures should be avoided. Where appropriate, it can be incorporated during the cooler stage of formulation processing according to the supplier's recommended procedure.
The manufacturer's technical documentation should be followed for exact incorporation temperature, concentration and handling conditions.
The appropriate pH range should be determined according to the specific commercial grade and finished formulation.
For peptide-based cosmetic systems, formulators should avoid unnecessarily extreme pH conditions and evaluate stability during formulation development.
Storage conditions depend on the supplied grade and presentation. Some commercial sh-Oligopeptide-1 materials are recommended for refrigerated storage, commonly around 2–8°C, while long-term storage may require lower temperatures.
The actual supplier TDS, SDS and COA should be followed for the specific material.
sh-Oligopeptide-1 can be considered for a variety of advanced cosmetic applications, including:
sh-Oligopeptide-1 is a recombinant human peptide used as a cosmetic skin-conditioning ingredient.
The INCI name is sh-Oligopeptide-1.
The CosIng record does not assign a CAS number to sh-Oligopeptide-1. Therefore, N/A / Not Assigned is the appropriate value when following the CosIng identity record.
The CosIng reference number is 87479.
The primary listed cosmetic function is Skin Conditioning.
Yes. sh-Oligopeptide-1 is a recombinant human peptide/protein ingredient.
The CosIng description specifies a maximum of 53 amino acids.
Yes. It can be considered for suitable peptide-based facial serum formulations.
Yes. It can be incorporated into suitable cosmetic cream and moisturizing formulations.
Storage requirements depend on the specific commercial grade. Refrigerated storage may be required for certain grades, and the supplier's technical documentation should be followed.
For the recombinant human EGF structure represented in PubChem, the molecular formula is C270H401N73O83S7 and the molecular weight is approximately 6,222 g/mol.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |