Swapnroop Pharma manufactures and supplies Polyvinylpyrrolidone (PVP) Excipient, also known as Povidone, a synthetic, water-soluble polymer widely used as a multifunctional pharmaceutical excipient.
Polyvinylpyrrolidone is a polymer of 1-vinyl-2-pyrrolidone and is identified by CAS No. 9003-39-8. The polymer is available in different viscosity grades characterized by their K-value, which is related to molecular weight and solution viscosity. USP describes Povidone as having a nominal K-value range from 10 to 120.
PVP is one of the most versatile pharmaceutical excipients because of its excellent water solubility, film-forming ability, binding properties and capacity to support dispersion and solubilization. It is commonly used in tablet, capsule, liquid, topical and other pharmaceutical formulations.
Polyvinylpyrrolidone is generally supplied as a white to almost white powder. Different PVP grades are selected according to their K-value and intended formulation function.
Common pharmaceutical grades include PVP K12, K15, K17, K25, K30, K60 and K90, with K30 being a widely used pharmaceutical binder grade.
Polyvinylpyrrolidone Excipient can be used as:
PVP's pharmaceutical applications include tablet and capsule binding, film formation, dispersion and suspension stabilization, as well as formulation support for poorly soluble ingredients.
The K-value is an important quality and grade characteristic of Povidone. USP specifies that Povidone has a nominal K-value from 10 to 120, and the K-value is stated on the product label.
Typical applications vary by grade:
Swapnroop Pharma supplies Polyvinylpyrrolidone (PVP) Pharmaceutical Excipient according to required grade and formulation requirements.
Because PVP grades have different K-values and corresponding physicochemical characteristics, the exact grade should be specified when preparing the product specification, CoA and regulatory documentation.
Polyvinylpyrrolidone Excipient should be stored in tightly closed containers in a cool, dry and clean environment. USP specifies preservation of Povidone in tight containers.
Protect the product from excessive moisture, contamination and unsuitable storage conditions.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |