Polyethylene Oxide (PEO) is a synthetic, high-molecular-weight polyether polymer composed of repeating ethylene oxide units. It is a water-soluble polymer used in pharmaceutical formulation development for its thickening, binding, film-forming, viscosity-modifying, mucoadhesive and controlled-release properties.
Polyethylene Oxide is closely related chemically to polyethylene glycol (PEG), but the two materials are generally distinguished by molecular-weight range and polymer characteristics. PEO typically refers to higher-molecular-weight polyethylene oxide materials, while PEG commonly refers to lower-molecular-weight grades.
Swapnroop Pharma manufactures and supplies Polyethylene Oxide in India for qualified pharmaceutical, nutraceutical, specialty formulation and industrial applications.
Polyethylene Oxide is a functional polymeric excipient that can provide controlled rheological and release characteristics in pharmaceutical formulations.
Depending on molecular weight and grade, it can function as:
PEO is particularly useful in controlled-release and extended-release dosage forms because its water-soluble polymer chains can hydrate and form a viscous gel layer.
Potential applications include:
The polymer's performance is influenced strongly by molecular weight, concentration, particle size and formulation composition.
High-molecular-weight Polyethylene Oxide can hydrate when exposed to aqueous media and form a viscous polymeric layer. This property can be used in matrix systems to help control the release of incorporated active ingredients.
The appropriate molecular-weight grade should be selected according to the desired hydration rate, gel strength, viscosity and drug-release profile.
Polyethylene Oxide has the repeating structure:
(–CH₂–CH₂–O–)ₙ
and can also be represented by the general formula:
(C₂H₄O)ₙ
It is a linear, water-soluble polyether polymer. Unlike low-molecular-weight PEG products, pharmaceutical PEO grades generally have substantially higher molecular weights.
It is typically supplied as a white or almost white powder or granules and is soluble or dispersible in water depending on molecular weight and formulation conditions.
Swapnroop Pharma supplies Polyethylene Oxide grades for pharmaceutical formulation and specialty applications. Grade selection can be aligned with requirements for:
Polyethylene Oxide should be stored in tightly closed, moisture-protective packaging in a cool, dry and clean environment. The material should be protected from excessive moisture, heat, contamination and incompatible conditions.
Storage should follow the applicable product specification and SDS.
Depending on the selected grade and customer requirements, documentation may include:
Swapnroop Pharma supplies Polyethylene Oxide for qualified pharmaceutical, nutraceutical and specialty formulation applications in India and international markets.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |