Polyethylene Glycol (PEG) is a synthetic, water-soluble polyether polymer widely used as a pharmaceutical excipient, solvent, co-solvent, plasticizer, humectant, lubricant, binder and formulation aid. PEG is available in a broad range of molecular weights, and its physical properties vary according to the selected grade.
Polyethylene Glycol is commonly identified by its approximate molecular weight, such as PEG 200, PEG 300, PEG 400, PEG 600, PEG 1000, PEG 1500, PEG 3350, PEG 4000 and PEG 6000. Selection of the appropriate grade depends on the desired viscosity, physical state, solubility and formulation function.
Swapnroop Pharma manufactures and supplies Polyethylene Glycol in India for qualified pharmaceutical, nutraceutical, cosmetic and specialty formulation applications.
PEG is a versatile excipient because its physical properties can be adjusted through molecular-weight selection.
Depending on the grade, PEG can function as:
PEG grades are widely used in different dosage forms. Lower molecular-weight PEG grades are generally liquids, while higher molecular-weight grades are semi-solid or solid materials.
Applications include:
PEG can also be combined with other excipients to adjust texture, viscosity, dissolution, moisture retention and processing characteristics.
The number associated with PEG generally indicates its approximate average molecular weight.
PEG 200 / PEG 300 / PEG 400:
Typically liquid grades used as solvents, vehicles, co-solvents and formulation aids.
PEG 600:
Generally a more viscous liquid or semi-solid material depending on temperature.
PEG 1000 and higher grades:
Generally semi-solid to solid/waxy materials used in applications such as binders, plasticizers, lubricants, carriers and suppository formulations.
PEG 3350, PEG 4000 and PEG 6000:
Higher-molecular-weight grades used in pharmaceutical formulations according to their individual pharmacopoeial and formulation requirements.
The exact grade should always be specified because PEG 400 and PEG 4000, for example, have substantially different physical and formulation properties.
Polyethylene Glycol has the general structure:
HO–(CH₂CH₂O)ₙ–H
It is a polymer of ethylene oxide and contains terminal hydroxyl groups.
PEG is highly hydrophilic and generally miscible or freely soluble in water, depending on molecular weight. Lower grades are typically clear, colourless, viscous liquids, while higher grades can occur as white or almost white waxy solids or flakes.
Swapnroop Pharma supplies pharmaceutical-grade Polyethylene Glycol to pharmaceutical manufacturers, formulation developers, nutraceutical companies and other qualified customers.
Grade selection can be aligned with requirements for:
Polyethylene Glycol should be stored in tightly closed, suitable packaging in a cool, dry and clean environment. The material should be protected from contamination, excessive heat and moisture where applicable.
Storage requirements should follow the approved specification and SDS of the selected PEG grade.
Depending on the selected grade and customer requirements, documentation may include:
Swapnroop Pharma supplies Polyethylene Glycol (PEG) for qualified pharmaceutical, nutraceutical, cosmetic and specialty formulation applications in India and international markets.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |