Piroctone Olamine is a specialty cosmetic ingredient consisting of the ethanolamine salt of Piroctone. It is widely recognized in personal-care formulations for its antimicrobial and scalp-care functionality, particularly in products developed for dandruff and scalp-condition management.
Piroctone Olamine has the CAS Number 68890-66-4 and a molecular weight of approximately 298.42 g/mol. Its chemical composition can be represented as C₁₄H₂₃NO₂ · C₂H₇NO, with the corresponding molecular formula C₁₆H₃₀N₂O₃. It is generally supplied as a white to almost-white crystalline powder.
The ingredient is particularly important in hair-care and scalp-care formulations, where its antimicrobial characteristics can complement the overall formulation strategy. Its use should always be considered in the context of the finished formulation, applicable regulations and the intended cosmetic claims.
Piroctone Olamine is also known as Piroctone Ethanolamine, Octopirox and Piroctone Olamine Salt. The primary CAS Number is 68890-66-4, while CAS 50650-76-5 is reported as a related CAS identifier for certain material records.
Its chemical composition is C₁₆H₃₀N₂O₃, with a molecular weight of 298.42 g/mol. The IUPAC identity describes it as a combination of Piroctone and 2-aminoethanol. Piroctone Olamine is normally encountered as a crystalline solid and is sensitive to excessive heat.
Current commercial analytical references report a white to almost-white powder or crystals, with one current specification reporting minimum 97.0 area% HPLC purity and a melting range of 134–138°C. Another analytical reference reports ≥99.0% HPLC assay. These values are grade-specific and should not be combined into a single universal commercial specification.
Piroctone Olamine is primarily valued for its antimicrobial functionality, particularly in scalp and hair-care formulations. Its use is strongly associated with products designed for dandruff and scalp-care applications.
The ingredient can be incorporated into formulations where control of microorganisms associated with scalp conditions is part of the formulation strategy. It is frequently considered for shampoos, scalp treatments and other hair-care preparations.
Piroctone Olamine should not, however, be treated simply as a universal preservative. Its role in a finished cosmetic product depends on the formulation objective, concentration, product category and applicable regulatory requirements.
Its compatibility with surfactants, conditioning agents, fragrances, emulsifiers and other functional ingredients should be assessed during formulation development. The final formulation should also undergo appropriate stability and microbiological evaluation.
Piroctone Olamine Cosmetic Ingredient is particularly relevant to anti-dandruff shampoos, scalp-care products, hair-care formulations, scalp lotions, cleansing products and specialty personal-care preparations.
Its use in hair-care systems is associated with formulations designed to support a clean and balanced scalp environment. It can be incorporated into shampoo systems and other topical formulations depending on the selected formulation technology.
Piroctone Olamine may also be considered for cosmetic systems where antimicrobial functionality is required as part of the overall product design. The actual use level should be determined during formulation development and according to the regulations applicable to the target market.
Because Piroctone Olamine is a solid ingredient with defined thermal characteristics, processing temperature should also be considered. Excessive heat should be avoided where the selected grade is specified as heat-sensitive.
Piroctone Olamine should be evaluated according to the specific commercial grade and analytical specification. Important quality parameters can include identity, HPLC purity, assay by titration where applicable, melting point, moisture, residue on ignition, heavy metals and related substances.
Current TCI information reports minimum 97.0 area% HPLC purity, minimum 97.0% by nonaqueous titration, and a melting range of 134–138°C. The same source identifies the material as heat-sensitive and recommends refrigerated storage at 0–10°C for its analytical grade.
Another current analytical standard reports ≥99.0% HPLC assay, demonstrating that purity requirements can vary by commercial grade and intended use.
Therefore, the SDP product specification should use the actual validated analytical method and acceptance limits applicable to the supplied material. An HPLC assay should only be stated where the actual product is tested by an appropriate validated HPLC method.
Piroctone Olamine is a specialty cosmetic ingredient with particular importance in hair-care and scalp-care formulation development. A reliable Piroctone Olamine Cosmetic Ingredient Manufacturer in India can provide material with defined identity, purity and physical characteristics for cosmetic manufacturers and formulators.
As a Piroctone Olamine manufacturer and supplier in India, Swapnroop can support bulk requirements for specialty cosmetic raw materials and personal-care ingredients. Product specifications can be established according to the required grade, application, analytical method and customer quality requirements.
For commercial formulation development, consistent control of HPLC purity, assay, appearance, melting range, moisture and related quality characteristics can help support batch-to-batch raw-material consistency.
| Parameter | Specification |
|---|---|
| Appearance | White or colourless crystals / white powder |
| Assay (HPLC) | NLT 97.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Water Content | NMT 0.5% |
| Melting Point | 134–138°C |