Oligopeptide-1 is a recombinant human epidermal growth factor (EGF)-related cosmetic ingredient used in advanced skin-care formulations. It is also known as sh-Oligopeptide-1 and is primarily classified as a skin-conditioning ingredient.
Oligopeptide-1 is used in cosmetic formulations such as serums, creams, lotions and other advanced skin-care products. Because it is a protein-based ingredient, formulation conditions, microbial control, storage temperature and stability are important considerations when developing products containing Oligopeptide-1.
Oligopeptide-1 is the cosmetic INCI name associated with recombinant human EGF. The recombinant protein contains approximately 53 amino-acid residues and has a molecular weight of approximately 6.2 kDa, depending on the analytical method and material specification.
CAS No.: 62253-63-8
INCI Name: Oligopeptide-1 / sh-Oligopeptide-1
Common Name: Epidermal Growth Factor (EGF)
Molecular Weight: Approximately 6.2 kDa
The CAS number 62253-63-8 is reported by multiple cosmetic and chemical ingredient sources for Oligopeptide-1/sh-Oligopeptide-1.
Oligopeptide-1 is used in advanced cosmetic formulations designed around skin conditioning and skin-care support.
Potential formulation formats include:
Because Oligopeptide-1 is a recombinant protein, its formulation requires greater attention to stability and contamination control than many conventional cosmetic raw materials.
Oligopeptide-1 is particularly associated with advanced skin-care formulations focused on the appearance and condition of the skin.
Potential applications include:
Cosmetic ingredient sources describe Oligopeptide-1 primarily as a skin-conditioning agent.
Important formulation parameters include:
Oligopeptide-1 is reported as water soluble. The exact handling and dilution procedure should follow the TDS for the commercial grade.
Oligopeptide-1 should generally be handled under controlled processing conditions because recombinant proteins can be sensitive to temperature and processing stress.
A commercial technical source reports a target pH range of approximately 5.5–7.0 for one sh-Oligopeptide-1 preparation. Another ingredient source reports approximately 4.0–7.0. Therefore, the final formulation pH should be established according to the specific commercial grade and formulation system.
Commercial preparations may require refrigerated storage at 2–8°C. Long-term storage requirements can differ by grade, so the supplier's SDS/TDS should be followed.
Oligopeptide-1 can be considered for:
Oligopeptide-1 is a recombinant human EGF-related cosmetic ingredient used primarily as a skin-conditioning agent.
The INCI identity is Oligopeptide-1, with sh-Oligopeptide-1 used for recombinant human EGF preparations.
The CAS number is 62253-63-8.
The recombinant protein has a molecular weight of approximately 6.2 kDa. PubChem reports approximately 6,222 g/mol for SH-Oligopeptide-1.
Oligopeptide-1 is primarily used as a skin-conditioning cosmetic ingredient in advanced skin-care formulations.
Yes. Oligopeptide-1 is reported as water soluble.
Yes. It can be incorporated into suitable serum and ampoule formulations.
Yes. It can be used in suitable cream and moisturizer formulations.
Storage depends on the commercial grade. Some recombinant Oligopeptide-1 preparations are recommended to be stored at 2–8°C.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |