Micronomicin is an aminoglycoside antibiotic and an analogue of gentamicin. It is also known as Gentamicin C2b and is associated with antibacterial activity against susceptible bacterial organisms. Micronomicin is an approved drug in Japan and has been used particularly in ophthalmic and systemic antibacterial applications.
Micronomicin is a specialized antibacterial pharmaceutical API belonging to the aminoglycoside class and is relevant to pharmaceutical development, microbiological research and formulation of antimicrobial products.
Micronomicin is a specialized aminoglycoside API requiring stringent control of identity, potency, related substances, moisture, residual solvents and microbiological quality.
CAS Number: 52093-21-7
Molecular Formula: C20H41N5O7
Molecular Weight: 463.58 g/mol
Chemical Class: Aminoglycoside Antibiotic
Synonym: Gentamicin C2b
Other Synonyms: Sagamicin, XK-62-2
Therapeutic Class: Aminoglycoside Antibacterial
Therapeutic Area: Infectious Diseases / Ophthalmology
Molecule Type: Natural Product / Aminoglycoside
PubChem and the Royal Society of Chemistry's Merck Index list the molecular formula as C20H41N5O7 and molecular weight at approximately 463.58 g/mol.
Micronomicin is an aminoglycoside antibacterial agent. Aminoglycosides exert their antibacterial effect primarily by binding to bacterial 30S ribosomal subunits, interfering with protein synthesis and causing production of abnormal proteins.
This results in:
Micronomicin API is associated with:
Micronomicin has been marketed in Japan and has been used in ophthalmic preparations; sources also describe systemic administration.
Micronomicin has been used in pharmaceutical preparations including:
Micronomicin is an aminoglycoside compound with high polarity. The reported molecular weight is 463.58 g/mol, and the compound has 12 defined stereocenters.
Micronomicin is a naturally derived aminoglycoside antibiotic. A controlled manufacturing process may involve:
Typical Micronomicin API quality testing may include:
Store Micronomicin API in a tightly closed pharmaceutical container, protected from excessive moisture, heat and direct light. Exact storage conditions should follow the validated stability data and applicable product specification.
Micronomicin is relevant to research involving:
Micronomicin is an aminoglycoside antibacterial agent, also known as Gentamicin C2b, with CAS Number 52093-21-7, molecular formula C20H41N5O7, and molecular weight 463.58 g/mol. It is associated particularly with ophthalmic antibacterial applications and is marketed in Japan.
| Parameter | Specification |
|---|---|
| Appearance | White crystalline powder or crystals |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 5.0 – 7.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |