Microcrystalline Cellulose (MCC) is a purified, partially depolymerized cellulose widely used as a multifunctional pharmaceutical excipient. It is particularly valued in tablet manufacturing because of its excellent binding, compactibility, flow and compression properties.
Swapnroop Pharma manufactures and supplies Microcrystalline Cellulose in India for pharmaceutical, nutraceutical and formulation applications. Different MCC grades can be selected according to particle size, bulk density, moisture, flow characteristics, compressibility and intended manufacturing process.
MCC is one of the most widely used excipients in oral solid dosage manufacturing. It can perform several formulation functions, including:
It is particularly suitable for direct compression, while selected grades are also used in wet granulation and dry granulation processes.
One of the major advantages of MCC is its excellent compressibility and compactibility. During tablet compression, MCC undergoes plastic deformation and can form strong compacts even at relatively low concentrations.
MCC can therefore help pharmaceutical manufacturers achieve:
Commercial MCC is available in different grades with different physical characteristics. Commonly encountered grades include MCC PH 101, PH 102, PH 105 and PH 200, although exact grade availability and specifications depend on the manufacturer.
Grade selection can influence:
Therefore, the appropriate MCC grade should be selected according to the formulation and manufacturing process.
Microcrystalline Cellulose is derived from highly purified cellulose and consists of partially depolymerized cellulose particles. It is primarily composed of β-(1→4)-linked D-glucose units.
MCC is generally supplied as a white or almost white, fine, free-flowing powder. It is practically insoluble in water and most organic solvents.
Because MCC is a cellulose-derived polymeric material, it does not have a single conventional molecular weight comparable to a small-molecule pharmaceutical ingredient.
Swapnroop Pharma supplies pharmaceutical-grade Microcrystalline Cellulose to pharmaceutical manufacturers, nutraceutical companies, tablet manufacturers and formulation developers.
The material can be supplied according to requirements for MCC grade, particle size, bulk density, moisture, flow properties, packaging, documentation and intended application.
Microcrystalline Cellulose should be stored in tightly closed, moisture-protective packaging in a cool, dry and clean environment.
The material should be protected from excessive humidity, contamination, heat and direct sunlight. Specific storage requirements should follow the applicable SDS, CoA, approved specification and manufacturer's recommendations.
Depending on the selected grade and customer requirements, documentation may include:
Swapnroop Pharma supplies Microcrystalline Cellulose for tablets, capsules, direct compression, granulation, nutraceutical and other oral solid dosage formulation applications in India and international markets.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |