Mepenzolic Acid API Manufacturer in India

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Mepenzolic Acid API

Mepenzolic Acid is a synthetic anticholinergic pharmaceutical compound that has been used as an antispasmodic agent. It acts primarily by reducing acetylcholine-mediated activity in gastrointestinal smooth muscle, helping to decrease intestinal spasms and excessive gastrointestinal motility.

Mepenzolic Acid is therefore associated mainly with gastrointestinal and antispasmodic pharmaceutical applications.

Mepenzolic Acid API Manufacturer in India

Mepenzolic Acid is a specialized gastrointestinal pharmaceutical API used in the development and manufacture of antispasmodic formulations.

Important quality attributes include identity, assay, related substances, water content, residual solvents, elemental impurities and stability characteristics, according to the applicable API specification.

Chemical Information

CAS Number: 25990-60-7
Molecular Formula: C21H29NO3
Molecular Weight: 343.46 g/mol
Chemical Name: Mepenzolic Acid
Drug Class: Anticholinergic / Antimuscarinic
Therapeutic Class: Antispasmodic
Therapeutic Area: Gastroenterology
Molecule Type: Synthetic Small Molecule

Mechanism of Action

Mepenzolic Acid produces anticholinergic effects by antagonizing muscarinic acetylcholine activity.

Reduction of cholinergic stimulation in the gastrointestinal tract can result in:

  • Reduced gastrointestinal smooth-muscle contraction
  • Decreased intestinal spasms
  • Reduced gastrointestinal motility
  • Reduction of excessive secretory activity

Pharmaceutical Applications

Mepenzolic Acid API is associated with pharmaceutical applications involving:

  • Gastrointestinal spasms
  • Intestinal cramping
  • Functional gastrointestinal disorders
  • Excessive gastrointestinal motility
  • Antispasmodic drug development
  • Gastrointestinal pharmacology research

Dosage Form Applications

Mepenzolic Acid has been used in pharmaceutical formulations such as:

  • Oral tablets
  • Oral capsules
  • Other oral antispasmodic preparations

The specific formulation depends on the pharmaceutical product and applicable regulatory requirements.

Physical Characteristics

Mepenzolic Acid is generally handled as a solid pharmaceutical substance. Its appearance, particle characteristics and solid-state properties should be controlled according to the applicable API specification.

Manufacturing Process

A controlled Mepenzolic Acid API manufacturing process may involve:

  1. Selection and qualification of starting materials
  2. Preparation of appropriate synthetic intermediates
  3. Controlled chemical synthesis
  4. Formation of the required molecular structure
  5. Purification
  6. Crystallization
  7. Filtration
  8. Controlled drying
  9. Milling or sieving where required
  10. Final analytical testing
  11. Pharmaceutical-grade packaging

Quality Control Testing

Typical Mepenzolic Acid API testing may include:

  • Identification by IR
  • HPLC identification
  • Assay by HPLC
  • Related substances
  • Water content
  • Residual solvents
  • Elemental impurities
  • Residue on ignition
  • Melting range
  • Particle-size distribution where applicable
  • Stability testing

Storage

Store Mepenzolic Acid API in a tightly closed container under controlled pharmaceutical storage conditions, protected from excessive moisture, heat and direct light.

Pharmaceutical Research

Mepenzolic Acid is relevant to research involving:

  • Muscarinic receptors
  • Anticholinergic pharmacology
  • Gastrointestinal smooth muscle
  • Intestinal motility
  • Gastrointestinal spasms
  • Antispasmodic drug development
  • Gastroenterology pharmaceutical research

Mepenzolic Acid API Summary

Mepenzolic Acid is a synthetic anticholinergic antispasmodic compound associated with gastrointestinal pharmaceutical applications. It has CAS Number 25990-60-7, molecular formula C21H29NO3, and molecular weight 343.46 g/mol.

Detailed Specifications

Parameter Specification
Appearance White to off-white crystalline powder
Identification IR & HPLC compliant
Assay (HPLC) 98.0% – 102.0%
Loss on Drying NMT 5.0%
Residue on Ignition NMT 0.5%
Heavy Metals NMT 10 ppm
pH (1% Solution) 5.0 – 7.0
Individual Impurity NMT 0.5%
Total Impurities NMT 2.0%
Water Content NMT 5.0%
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