Lisuride is a synthetic ergoline derivative and dopamine receptor agonist used as an active pharmaceutical ingredient in pharmaceutical formulations and drug-development applications. It also interacts with selected serotonin receptors and has been studied for its effects on dopaminergic and prolactin-regulating pathways.
Lisuride has the CAS Number 18016-80-3, molecular formula C20H26N4O and molecular weight 338.40 g/mol. It belongs to the ergoline derivative class and is chemically characterized as a dopamine agonist.
Lisuride is a synthetic ergot-derived compound with dopaminergic activity. It primarily acts as a dopamine receptor agonist and also interacts with different serotonin receptor subtypes. Its pharmacological properties have supported its use and research in Parkinson's disease and other dopamine-related conditions.
Lisuride is a chemically defined small molecule with specific stereochemical characteristics. Its chemical identity, purity and stereochemistry are important quality attributes for pharmaceutical API characterization.
Lisuride acts primarily as a dopamine receptor agonist and also interacts with serotonin receptors, including selected 5-HT receptor subtypes. Its dopaminergic activity influences neurotransmission in pathways associated with movement and endocrine regulation.
Lisuride can be characterized using validated chromatographic and spectroscopic analytical methods. HPLC may be used for assay and related-substance determination, while suitable spectroscopic and chromatographic techniques can be used for identity testing.
Quality control may include identity, assay, related substances, water content, residual solvents, elemental impurities and other applicable parameters according to the approved product specification.
Lisuride should be stored in a tightly closed container under controlled pharmaceutical storage conditions. The material should be protected from excessive heat, moisture, direct light and contamination. Specific storage requirements should follow the applicable product specification and Certificate of Analysis.
Lisuride API may be supplied for pharmaceutical manufacturing, formulation development, analytical testing, neuropharmacology research and other qualified pharmaceutical applications. Product specifications, Certificate of Analysis, packaging configuration and regulatory documentation should be confirmed according to the intended application.
Swapproop Drugs and Pharmaceuticals supports the sourcing and supply of Lisuride API for qualified pharmaceutical and research requirements. Customers can request product specifications, analytical documentation, Certificate of Analysis, packaging information and commercial details.
For Lisuride API requirements in India, contact Swapproop Drugs and Pharmaceuticals for product availability and technical information.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 2.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |