Liothyronine Sodium is the sodium salt of liothyronine, also known as L-triiodothyronine (T3), a synthetic thyroid hormone. It is an active pharmaceutical ingredient used in thyroid hormone replacement formulations and pharmaceutical development.
Liothyronine Sodium has the CAS Number 55-06-1, molecular formula C15H11I3NNaO4 and molecular weight 672.95 g/mol. It is the sodium salt of the biologically active thyroid hormone triiodothyronine.
Liothyronine Sodium is a synthetic form of the naturally occurring thyroid hormone L-triiodothyronine (T3). Compared with thyroxine (T4), T3 has a more rapid onset of biological activity and plays an important role in regulating metabolism, growth and development.
Liothyronine Sodium is characterized by its high iodine content and stereospecific structure. It is used as an active pharmaceutical ingredient in thyroid hormone replacement products and is subject to stringent pharmaceutical quality and analytical requirements.
Liothyronine Sodium provides synthetic L-triiodothyronine (T3). Thyroid hormones enter cells and bind to nuclear thyroid hormone receptors, which regulate DNA transcription and protein synthesis. Through these mechanisms, thyroid hormones influence metabolism, growth and development.
Swapproop Drugs and Pharmaceuticals supports the sourcing and supply of Liothyronine Sodium API for qualified pharmaceutical requirements. The API can be evaluated according to applicable pharmacopoeial standards and customer-specific quality requirements.
For Liothyronine Sodium API availability, technical documentation, specifications and commercial requirements, contact Swapproop Drugs and Pharmaceuticals.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 97.0% – 103.0% on anhydrous basis |
| Loss on Drying | NMT 4.0% |
| Residue on Ignition | NMT 0.5% |
| Water Content | NMT 4.0% |