Levomethadyl Acetate, also known as Levacetylmethadol or LAAM, is a synthetic opioid compound and acetate ester of levomethadyl. It is a long-acting opioid with activity at opioid receptors and has historically been associated with the treatment of opioid dependence.
Levomethadyl Acetate has the CAS Number 1477-40-3, molecular formula C23H31NO2 and molecular weight 353.5 g/mol. It is chemically identified as [(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate.
Levomethadyl Acetate is a synthetic opioid compound structurally related to methadone and methadol. It produces prolonged opioid receptor activity through its parent compound and active metabolites. The compound has been investigated and used historically in opioid dependence treatment.
Levomethadyl Acetate is a controlled substance, and its manufacture, handling, storage, distribution and use are subject to applicable controlled-substance laws and regulatory requirements.
Levomethadyl Acetate is a synthetic opioid that produces pharmacological effects through interaction with opioid receptors. Its activity is associated primarily with the mu-opioid receptor system. Levomethadyl Acetate is metabolized to active compounds that contribute to its prolonged opioid activity.
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Levomethadyl Acetate has CAS Number 1477-40-3, molecular formula C23H31NO2 and molecular weight 353.5 g/mol. Its PubChem Compound ID is 15130 and its FDA UNII is R3B637Y991.
Levomethadyl Acetate is classified as a controlled substance in the United States. Supply, possession, manufacture, import, export and distribution are subject to applicable controlled-substance regulations and licensing requirements.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Individual Impurity | ≤ 0.5% |
| Total Impurities | ≤ 1.5% |
| Water Content | NMT 1.0% |