Ifupinostat is a small-molecule investigational pharmaceutical compound associated with inhibition of histone deacetylases (HDACs). HDACs are enzymes involved in the regulation of chromatin structure and gene expression, making them important targets in research involving cancer and other disease pathways.
Ifupinostat has been investigated primarily as a histone deacetylase inhibitor (HDAC inhibitor) and has been studied in oncology-focused pharmaceutical research.
Ifupinostat is a specialized small-molecule research and pharmaceutical-development compound requiring controlled synthesis, purification and analytical characterization. Quality assessment may include identity, assay, related substances, residual solvents, water content, elemental impurities and other process-related impurities.
The availability, regulatory status and permitted application of Ifupinostat may vary by jurisdiction and development stage.
CAS Number: 201900-47-8
Molecular Formula: C22H28N2O3
Molecular Weight: 368.48 g/mol
Drug Class: Histone Deacetylase Inhibitor
Pharmacological Class: HDAC Inhibitor
Therapeutic Class: Investigational Antineoplastic Agent
Therapeutic Area: Oncology / Cancer Research
Ifupinostat is associated with inhibition of histone deacetylase activity.
HDAC enzymes remove acetyl groups from histone and other proteins, influencing chromatin organization and gene transcription. Inhibition of HDAC activity can alter gene expression and cellular signaling pathways involved in cell proliferation, differentiation and apoptosis.
These mechanisms make HDAC inhibitors an important area of oncology research.
Ifupinostat has been investigated in research related to:
Because Ifupinostat is an investigational compound, its research applications should not be represented as established approved therapeutic indications.
Epigenetic regulation plays an important role in cancer biology. HDAC inhibition can influence transcriptional activity and cellular differentiation, providing a basis for investigating HDAC inhibitors as potential anticancer agents.
Ifupinostat is therefore of interest in preclinical and clinical pharmaceutical research involving epigenetic cancer therapies.
Ifupinostat is a synthetic organic small molecule containing nitrogen- and oxygen-containing functional groups. It is generally handled as a pharmaceutical research compound and requires appropriate analytical characterization to confirm identity, purity and stability.
Ifupinostat API/research-grade material quality evaluation may include:
Ifupinostat should be stored in a tightly closed container under controlled conditions and protected from excessive heat, moisture and direct light. Final storage conditions should be established from validated stability data.
Ifupinostat is relevant to research involving HDAC inhibition, epigenetic regulation, chromatin biology and targeted anticancer drug development.
Ifupinostat is an investigational histone deacetylase inhibitor with CAS Number 201900-47-8, molecular formula C22H28N2O3, and molecular weight 368.48 g/mol. It is primarily of interest in pharmaceutical research involving HDAC inhibition, epigenetic regulation and oncology.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 4.0 – 7.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |