Hydroxypropyl Methylcellulose Phthalate (HPMCP) is a cellulose-derived pharmaceutical excipient and enteric polymer used primarily in oral pharmaceutical formulations. It is a chemically modified cellulose ether containing methoxy, hydroxypropoxy, and phthalyl groups.
HPMCP is designed to provide pH-dependent dissolution, making it suitable for enteric coatings and delayed-release dosage forms. It remains resistant to dissolution under acidic gastric conditions and dissolves more readily at higher pH conditions encountered in the intestinal environment.
Swapnroop Pharma manufactures and supplies Hydroxypropyl Methylcellulose Phthalate in India for pharmaceutical formulation, enteric coating, delayed-release, and advanced drug-delivery applications.
Hydroxypropyl Methylcellulose Phthalate is used in:
One of the primary functions of HPMCP is its use as an enteric coating polymer. Its phthalyl groups provide pH-dependent solubility, allowing coated dosage forms to resist dissolution in acidic gastric fluid and subsequently dissolve under appropriate intestinal pH conditions.
This property makes HPMCP useful when an API needs protection from gastric conditions or when release in the upper gastrointestinal tract needs to be controlled.
HPMCP can be incorporated into coating systems for tablets, capsules, pellets, and granules to create delayed-release pharmaceutical dosage forms.
Different grades can provide different dissolution characteristics. Grade selection should therefore consider the desired release location, API characteristics, coating process, polymer concentration, and target dissolution profile.
HPMCP is a semi-synthetic cellulose derivative prepared by esterification of hydroxypropyl methylcellulose with phthalic groups.
Because it is a substituted polymer, HPMCP does not have one simple fixed molecular formula or molecular weight. Its performance depends on parameters such as:
Swapnroop Pharma provides Hydroxypropyl Methylcellulose Phthalate manufacturing and supply solutions in India for pharmaceutical manufacturers, formulation developers, and qualified bulk customers.
Our HPMCP supply is intended for applications including enteric coating, delayed-release formulations, gastro-resistant dosage forms, pellets, granules, and specialized oral drug-delivery systems.
Material specifications, packaging, documentation, and supply quantities can be aligned with customer and pharmaceutical-grade requirements.
HPMCP should be stored in tightly closed, moisture-protective packaging in a cool, dry and clean environment. It should be protected from excessive humidity, heat, direct sunlight, and contamination.
Storage and handling should follow the applicable SDS, CoA, product specification, and manufacturer's recommendations.
Depending on the grade and customer requirements, documentation may include:
Swapnroop Pharma supplies Hydroxypropyl Methylcellulose Phthalate (HPMCP) as a specialized pharmaceutical excipient and enteric polymer for modern oral drug-delivery and delayed-release formulation applications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |