Glucosamine HCl, also known as Glucosamine Hydrochloride, is the hydrochloride salt of glucosamine, an amino sugar that occurs naturally in biological systems and forms part of the structural building blocks of several important polysaccharides.
Glucosamine HCl is a defined chemical ingredient with the molecular formula C₆H₁₄ClNO₅ and a molecular weight of approximately 215.63 g/mol. The commonly assigned CAS Number is 66-84-2.
In cosmetic and personal-care applications, Glucosamine HCl can be considered a specialty amino-sugar-derived ingredient for skin-care formulations. It is particularly relevant to formulations containing carbohydrate-derived, amino-sugar or glycosaminoglycan-related ingredients.
Glucosamine HCl should be clearly distinguished from N-Acetyl Glucosamine (NAG). Although both are glucosamine derivatives, they are chemically different materials with different molecular formulas, CAS numbers and technical identities.
Glucosamine HCl is the hydrochloride salt of glucosamine. Glucosamine contains an amino group and several hydroxyl groups, while the hydrochloride form contains hydrochloride associated with the amino group.
The chemical identity can be summarized as follows:
Glucosamine HCl is a defined small molecule rather than a polymeric material. This makes its identity and purity more straightforward to characterize than complex materials such as Hydrolyzed DNA, Chondroitin Sulfate or Sodium Hyaluronate.
The source of glucosamine should also be considered. Commercial material may be manufactured from different starting materials, and source information should be documented according to the specific grade.
Glucosamine HCl is a specialty ingredient that can be incorporated into cosmetic formulations where an amino-sugar-derived raw material is required.
Its chemical structure contains several hydrophilic functional groups, allowing it to participate in appropriately designed aqueous cosmetic systems.
Glucosamine HCl can be considered for:
When formulating with Glucosamine HCl, the selected concentration, pH, solubility and compatibility with other ingredients should be evaluated.
It is important not to automatically transfer the documented functions or claims of N-Acetyl Glucosamine to Glucosamine HCl. These are separate ingredients and should be presented independently on an ingredient website.
Glucosamine HCl can be considered for specialty facial formulations where amino-sugar-derived ingredients are incorporated.
It may be used in formulations such as:
Glucosamine HCl can also be incorporated into ingredient blends containing other carbohydrate-derived and skin-conditioning materials.
Potential complementary ingredients include:
Compatibility should be confirmed through formulation testing rather than assumed solely from chemical classification.
| Parameter | Specification |
|---|---|
| Appearance | White or colourless crystals / white powder |