Garenoxacin API Manufacturer in India

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Garenoxacin API Manufacturer and Bulk Supplier in India

Garenoxacin API (CAS No: 194804-75-6)

Broad-Spectrum Quinolone Antibacterial API for Respiratory and Anti-Infective Pharmaceutical Formulations

Garenoxacin API (CAS No. 194804-75-6) is a synthetic quinolone antibacterial pharmaceutical active ingredient associated with broad-spectrum anti-infective and respiratory pharmaceutical applications.

Garenoxacin is a des-fluoro(6) quinolone antibacterial agent developed to provide antibacterial activity against susceptible Gram-positive and Gram-negative microorganisms.

Garenoxacin acts by inhibiting bacterial DNA topoisomerase IV and DNA gyrase. These bacterial enzymes are essential for DNA replication and maintenance. Inhibition of these enzymes interferes with bacterial DNA replication and prevents susceptible bacteria from growing and multiplying.

Pharmaceutical companies sourcing Garenoxacin API commonly evaluate assay, HPLC purity, stereochemical identity, related substances, process-related impurities, degradation products, residual solvents, water content, crystalline characteristics, particle size distribution, and batch-to-batch consistency.

Because Garenoxacin contains a defined chiral center, stereochemical identity and chiral purity are important quality considerations during API qualification. Pharmaceutical buyers may evaluate specific rotation, enantiomeric purity, chromatographic purity, process-related impurities, and consistency of the API impurity profile.

Garenoxacin free compound and Garenoxacin Mesilate or Mesylate Hydrate should be treated as separate pharmaceutical material identities. Procurement, quality, and regulatory teams should confirm the exact required chemical form before commercial sourcing.

Swapnroop Drugs and Pharmaceuticals supplies Garenoxacin API for qualified pharmaceutical research, formulation development, analytical, antibacterial drug development, and regulated manufacturing requirements with product-specific quality documentation, pharmaceutical-grade packaging, and reliable supply-chain coordination.

 

 

 

Critical Quality Requirements for Garenoxacin API

Pharmaceutical companies evaluating Garenoxacin API commonly focus on:

  • HPLC assay and chromatographic purity
  • Chemical identity
  • Stereochemical identity
  • Chiral purity
  • Enantiomeric impurity control
  • Specific optical rotation
  • Related substances
  • Process-related impurity control
  • Degradation product monitoring
  • Residual solvent profile
  • Water and moisture content
  • Elemental impurity assessment
  • Crystal-form consistency
  • Particle size distribution
  • Powder handling characteristics
  • Batch-to-batch consistency
  • Stability under recommended storage conditions

Stereochemical consistency is particularly important for Garenoxacin API because the molecule contains a defined R-configuration.

Impurity-profile control is also an important API qualification consideration. Process-related impurities, degradation products, residual solvents, and enantiomeric impurities should be evaluated according to the approved product specification and applicable regulatory requirements.

Key Features

  • Garenoxacin API CAS No. 194804-75-6
  • Synthetic broad-spectrum antibacterial active ingredient
  • Quinolone antibacterial pharmaceutical compound
  • Des-fluoro(6) quinolone class
  • DNA gyrase inhibitor
  • DNA topoisomerase IV inhibitor
  • Molecular formula C23H20F2N2O4
  • Molecular weight 426.4 g/mol
  • Defined R-stereochemical configuration
  • Controlled HPLC purity profile
  • Chiral purity monitoring
  • Enantiomeric impurity control
  • Related substances monitored according to approved specification
  • Process and degradation impurity monitoring
  • Crystal-form consistency evaluation
  • Particle size requirements coordinated as applicable
  • Residual solvents controlled according to applicable ICH Q3C requirements
  • Elemental impurities evaluated according to applicable ICH Q3D requirements
  • Pharmaceutical-grade packaging
  • COA and MSDS available as applicable
  • Bulk pharmaceutical supply and export coordination

Applications of Garenoxacin API

Garenoxacin API is primarily associated with:

  • Broad-spectrum antibacterial pharmaceutical development
  • Respiratory antibacterial drug development
  • Community-acquired pneumonia pharmaceutical research
  • Acute bacterial sinusitis pharmaceutical development
  • Bronchitis-related antibacterial research
  • Respiratory tract infection drug development
  • Quinolone antibacterial pharmaceutical research
  • DNA gyrase inhibitor research
  • Topoisomerase IV inhibitor research
  • Oral antibacterial formulation development
  • Anti-infective analytical research
  • Pharmaceutical formulation development
  • Approved pharmaceutical manufacturing requirements

Garenoxacin-related pharmaceutical products have been evaluated for susceptible bacterial infections, particularly respiratory and other anti-infective applications.

Garenoxacin API for Antibacterial Pharmaceutical Development

Garenoxacin is a synthetic quinolone antibacterial compound associated with inhibition of bacterial DNA replication.

Pharmaceutical formulation companies evaluating Garenoxacin API may review:

  • API assay
  • HPLC purity
  • Chemical identification
  • Stereochemical identity
  • Chiral purity
  • Enantiomeric impurity
  • Specific rotation
  • Related substance profile
  • Process-related impurities
  • Degradation products
  • Residual solvents
  • Moisture content
  • Crystal form
  • Particle size distribution
  • Formulation compatibility
  • Stability data
  • Batch-to-batch consistency

Product-specific API specifications should be evaluated according to the intended dosage form, target regulatory market, formulation technology, and approved pharmaceutical development requirements.

Garenoxacin Mechanism of Antibacterial Activity

Garenoxacin targets bacterial DNA topoisomerase IV and DNA gyrase.

These enzymes are required for bacterial DNA replication, chromosome separation, and maintenance of DNA topology.

Inhibition of bacterial topoisomerase activity interferes with DNA replication and bacterial cell multiplication.

The dual targeting of DNA gyrase and topoisomerase IV is an important pharmacological characteristic of Garenoxacin and other quinolone-class antibacterial compounds.

Garenoxacin and Garenoxacin Mesilate Hydrate

Garenoxacin and Garenoxacin Mesilate Hydrate should be treated as separate pharmaceutical material identities.

Garenoxacin free compound has CAS No. 194804-75-6, molecular formula C23H20F2N2O4, and molecular weight approximately 426.4 g/mol.

Garenoxacin Mesilate Hydrate is a mesilate salt hydrate form associated with marketed pharmaceutical products in Japan.

Procurement, formulation, quality, and regulatory teams should confirm the exact free compound, mesilate, mesylate, or hydrate form before commercial sourcing.

Why Choose Swapnroop for Garenoxacin API?

Swapnroop Drugs and Pharmaceuticals supports qualified pharmaceutical and research customers with:

  • Reliable Garenoxacin API supply coordination
  • Product-specific specification support
  • COA and MSDS availability as applicable
  • Technical documentation coordination
  • Chiral purity requirement coordination
  • Related substance specification support
  • Secure pharmaceutical-grade packaging
  • Bulk quantity supply support
  • Particle size requirement coordination as applicable
  • Export documentation assistance
  • Global pharmaceutical supply coordination
  • Dedicated commercial enquiry support
  • Support for antibacterial pharmaceutical and formulation development requirements

Packaging & Supply

Garenoxacin API is supplied in secure pharmaceutical-grade packaging selected according to product quantity, stability requirements, moisture protection requirements, and customer specifications.

Product-appropriate inner polyethylene liners and approved pharmaceutical-grade outer containers or HDPE drums may be used according to the supplied material specification.

Available packaging configurations may include:

  • 1 kg packaging
  • 5 kg packaging
  • 10 kg packaging
  • 25 kg packaging
  • Customer-specific packaging as applicable

Packaging configuration, MOQ, commercial quantity, particle size requirements, and shipment conditions are confirmed according to the approved product specification and customer enquiry.

Storage and Handling

Store Garenoxacin API in tightly closed and appropriately labeled containers under the controlled storage conditions specified in the approved product documentation.

Protect the material from excessive moisture, heat, direct light, and unsuitable environmental exposure.

Handling should be performed by trained personnel using approved pharmaceutical raw material handling procedures and applicable safety documentation.

Product-specific storage and handling requirements should be confirmed from the approved COA, SDS, specification, and stability documentation.

Garenoxacin API Manufacturer and Supplier in India

Swapnroop Drugs and Pharmaceuticals provides Garenoxacin API bulk supply and export support in India for qualified pharmaceutical manufacturers, antibacterial formulation developers, generic drug companies, analytical laboratories, research organizations, and pharmaceutical procurement customers.

For Garenoxacin API price, CAS No. 194804-75-6, specification, HPLC purity, chiral purity, related substance profile, COA availability, MOQ, packaging, and export enquiries, contact our pharmaceutical sales team.

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