Furaltadone Hydrochloride API is the hydrochloride salt of furaltadone, a synthetic nitrofuran antimicrobial compound. Furaltadone belongs to the nitrofuran class of antibacterial agents and has historically been used primarily in veterinary and animal-health applications. The hydrochloride form is also known as Furaltadone HCl and NF-902 hydrochloride.
Furaltadone Hydrochloride has the molecular formula C₁₃H₁₇ClN₄O₆ and molecular weight 360.75 g/mol. The free-base form of furaltadone is different, with CAS 139-91-3, molecular formula C₁₃H₁₆N₄O₆, and molecular weight 324.29 g/mol.
Furaltadone Hydrochloride is described as a yellow crystalline powder in its monohydrate form, while the anhydrous material is described as a white crystalline powder. A technical datasheet reports a melting point of approximately 240°C with decomposition.
| Property | Value |
|---|---|
| API Name | Furaltadone Hydrochloride |
| Synonym | Furaltadone HCl |
| CAS Number | 3759-92-0 |
| Molecular Formula | C₁₃H₁₇ClN₄O₆ |
| Molecular Weight | 360.75 g/mol |
| Free Base CAS | 139-91-3 |
| Free Base Molecular Weight | 324.29 g/mol |
| Chemical Class | Nitrofuran antimicrobial |
| Salt Form | Hydrochloride |
| Physical Form | Yellow crystalline powder |
| Melting Point | Approx. 240°C, with decomposition |
Furaltadone belongs to the 5-nitrofuran antimicrobial group. Nitrofurans undergo reduction within susceptible microorganisms, producing reactive intermediates that can damage bacterial cellular components and interfere with essential biological processes.
The compound has historically demonstrated activity against a broad range of Gram-positive and Gram-negative bacteria. A technical Furaltadone Hydrochloride datasheet describes activity against organisms including Salmonella, Escherichia, Proteus, Streptococcus and Staphylococcus.
Furaltadone Hydrochloride has historically been associated mainly with veterinary antimicrobial applications. It has been used in animal-health products and has also been listed in regulatory contexts concerning veterinary drugs.
A FUJIFILM Wako reference-standard listing identifies Furaltadone Hydrochloride as a standard for veterinary drugs and for HPLC analysis.
Potential API applications include:
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | NLT 98.0% by HPLC |
| Loss on Drying | NMT 5.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |
| Melting Point | Approx. 240°C |