Fluvoxamine Maleate is a selective serotonin reuptake inhibitor (SSRI) belonging to the chemical class of 2-aminoethyl oxime ethers of aralkylketones. It is the maleate salt of fluvoxamine and is used as an active pharmaceutical ingredient in oral pharmaceutical formulations.
Fluvoxamine Maleate is primarily used in the treatment of obsessive-compulsive disorder (OCD). Its pharmacological activity is associated with potent inhibition of the serotonin reuptake transporter, increasing serotonin availability in the brain.
Fluvoxamine Maleate is described as a white to off-white, odorless crystalline powder. It is sparingly soluble in water, freely soluble in ethanol and chloroform, and practically insoluble in diethyl ether.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Heavy Metals | NMT 10 ppm |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |