Fluspirilene API is a synthetic diphenylbutylpiperidine derivative belonging to the class of typical antipsychotic compounds. It is identified by CAS Number 1841-19-6, with the molecular formula C₂₉H₃₁F₂N₃O and molecular weight 475.57 g/mol.
Fluspirilene is chemically identified as 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one. It is a solid material and is reported as white to yellow in appearance.
Fluspirilene has a molecular formula of C₂₉H₃₁F₂N₃O and molecular weight of 475.57 g/mol. The compound is achiral and has no defined stereocenters.
The reported melting point is 187.5–190°C. Fluspirilene is insoluble in water and soluble in DMSO; Sigma-Aldrich also reports solubility in ethanol.
Commercial analytical material is available with an HPLC assay of ≥98.0%. Sigma-Aldrich identifies the material as a solid, white in color, with an assay of ≥98% by HPLC.
For pharmaceutical-quality Fluspirilene, quality control may include identification, assay, related substances, loss on drying, residue on ignition and other applicable analytical tests. The exact release specification should correspond to the approved manufacturer specification and batch Certificate of Analysis.
Fluspirilene is a long-acting antipsychotic compound belonging to the diphenylbutylpiperidine class. It has been used in pharmaceutical applications associated with the treatment of schizophrenia.
Fluspirilene API may be supplied for pharmaceutical research, development and manufacturing applications subject to applicable regulatory requirements, quality standards and documentation.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | NLT 98.0% by HPLC |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 10 ppm |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |
| Melting Point | 187.5–190°C |
| Solubility | Insoluble in water; soluble in DMSO; soluble in ethanol |