Faropenem is an orally active beta-lactam antibacterial agent belonging to the penem class. It has a broad antibacterial spectrum and is structurally characterized by a penem nucleus containing a tetrahydrofuran substituent. Faropenem is identified by CAS Number 106560-14-9, with the molecular formula C₁₂H₁₅NO₅S and molecular weight 285.32 g/mol.
Faropenem API is used as an active pharmaceutical ingredient in the development and manufacture of pharmaceutical formulations. As a penem-class beta-lactam antibiotic, Faropenem exhibits antibacterial activity against a range of Gram-positive and Gram-negative organisms. Its chemical and pharmaceutical properties make it an important API for antibacterial drug development and manufacturing.
Faropenem has the molecular formula C₁₂H₁₅NO₅S and a molecular weight of 285.32 g/mol. Its CAS Registry Number is 106560-14-9, and its FDA GSRS UNII is F52Y83BGH3. The systematic IUPAC name is (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid.
Faropenem is associated with oral antibacterial pharmaceutical formulations and has been investigated for bacterial infections, including respiratory and urinary tract infections. It belongs to the penem group of beta-lactam antibacterial agents and demonstrates activity against a range of bacterial organisms.
Faropenem API should be manufactured, tested and released according to the applicable quality specifications established for the particular API grade and manufacturing process. Typical quality evaluation may include identification, assay by HPLC, related substances, water content, residue on ignition and other applicable physicochemical and microbiological quality attributes.
The exact acceptance criteria should always be based on the current approved specification and Certificate of Analysis (COA) for the supplied material.
We provide information and supply support for Faropenem API for pharmaceutical and formulation manufacturing requirements. Faropenem can be supplied subject to applicable quality, regulatory, documentation and commercial requirements.
For Faropenem API requirements, customers can contact us for product availability, technical documentation, specifications, COA and commercial details.
Faropenem sodium should not be confused with Faropenem free acid. Faropenem sodium has CAS Number 122547-49-3, molecular formula C₁₂H₁₄NNaO₅S, and molecular weight 307.30 g/mol on an anhydrous basis.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 5.5 – 6.5 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |