Enrofloxacin is a synthetic fluoroquinolone antibacterial agent primarily used in veterinary medicine. It exhibits broad-spectrum antibacterial activity against susceptible Gram-negative and Gram-positive bacteria and is commonly used in veterinary pharmaceutical formulations.
Enrofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription and repair. This interference ultimately results in bacterial cell death.
Enrofloxacin is a fluorinated quinolone derivative developed specifically for veterinary applications. It is used in veterinary medicines for the management of susceptible bacterial infections in various animal species.
Enrofloxacin has the molecular formula C₁₉H₂₂FN₃O₃ and a molecular weight of approximately 359.40 g/mol.
Swapnroop Drugs and Pharmaceuticals provides Enrofloxacin API for qualified veterinary pharmaceutical manufacturing, formulation development, research and pharmaceutical sourcing requirements.
Enrofloxacin is a specialized veterinary antibacterial API belonging to the fluoroquinolone class.
Enrofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes regulate bacterial DNA topology and are essential for DNA replication and transcription. Their inhibition interferes with bacterial DNA synthesis and produces a bactericidal effect.
Enrofloxacin is associated with:
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 2.0% |
| Water Content | NMT 1.0% |