Edrophonium is a short-acting, reversible acetylcholinesterase inhibitor. It increases the availability of acetylcholine at cholinergic synapses by temporarily inhibiting the enzyme responsible for acetylcholine breakdown. Edrophonium has been associated with neuromuscular and diagnostic applications.
Edrophonium is also known as edrophonium chloride when supplied as its commonly used salt form. It has been used in clinical settings for evaluating neuromuscular transmission and as a short-acting acetylcholinesterase inhibitor.
Swapnroop Drugs and Pharmaceuticals provides Edrophonium API for pharmaceutical development and manufacturing applications, subject to applicable quality specifications and regulatory requirements.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 2.0% |
| Water Content | NMT 1.0% |
| Melting Point | 150°C – 154°C |