Domperidone SR Pellets Manufacturer in India

Swapnroop Pharma · WHO-GMP Certified · +91 87670 62101

Domperidone SR Pellets

Pharmaceutical-Grade Domperidone Sustained-Release Pellets for Oral Multiparticulate Formulations

Domperidone SR Pellets are pharmaceutical-grade sustained-release multiparticulate pellets containing Domperidone as the active ingredient. Domperidone has CAS Number 57808-66-9, molecular formula C₂₂H₂₄ClN₅O₂, and molecular weight 425.91 g/mol.

The sustained-release pellet format is designed to modify the release of Domperidone over a defined period compared with an immediate-release pellet system. The release profile is achieved through the pellet composition and/or functional coating system, with the final dissolution behavior controlled according to the applicable product specification.

Commercial pharmaceutical pellet portfolios report 20% and 30% w/w Domperidone SR Pellets as established commercial strengths. Some manufacturers additionally list 40% formulations. These commercial values should not automatically be treated as SDP-approved strengths unless they match the current SDP product specification.

For SDP, the final Domperidone loading, dissolution profile, particle-size distribution, moisture and other release parameters should be controlled according to the applicable product specification.

Key Features

  • Pharmaceutical-grade Domperidone SR Pellets
  • Sustained-release multiparticulate format
  • Domperidone-based pellet formulation
  • Suitable for oral multiparticulate formulations
  • Suitable for capsule-filling applications
  • Controlled release characteristics
  • Product-specific Domperidone active loading
  • Product-specific particle-size distribution
  • Suitable for formulation development
  • Suitable for bulk pharmaceutical supply

Sustained-Release Pellet Technology

Domperidone SR Pellets use a formulation approach intended to provide a prolonged release profile. The final release behavior depends on factors such as active loading, pellet-core composition, polymeric coating system, coating level, pellet size and dissolution conditions.

Because these variables differ between products, a single universal dissolution specification should not be assigned to every Domperidone SR Pellet.

Commercially documented Domperidone SR pellet strengths include 20% and 30% w/w, with additional commercial listings reporting 40% formulations.

 Why Domperidone SR Pellets from Swapnroop?

  • Pharmaceutical-Grade Pellets: Designed for pharmaceutical formulation applications.
  • Sustained-Release Format: Suitable for sustained-release multiparticulate formulations.
  • Product-Specific Active Loading: Domperidone concentration is established according to the applicable product specification.
  • Multiparticulate Format: Suitable for capsule-filling and oral formulation development.
  • Controlled Pellet Characteristics: Particle size and other physical parameters can be controlled according to product requirements.
  • Controlled Release Profile: Release characteristics are established according to the applicable formulation and dissolution specification.
  • Formulation Flexibility: Suitable for different formulation-development requirements.
  • Bulk Pharmaceutical Supply: Suitable for pharmaceutical manufacturing and formulation requirements.

 Applications

Domperidone SR Pellets can be used for:

  • Sustained-release oral formulations
  • Multiparticulate capsule formulations
  • Capsule-filling applications
  • Sustained-release pellet systems
  • Oral pharmaceutical formulation development
  • Functional coating applications
  • Customized release-profile formulations
  • Multiparticulate formulation development
  • Bulk pharmaceutical manufacturing

Detailed Specifications

Parameter Specification
Appearance white to off-white crystalline powder
Identification IR & HPLC compliant
Assay (HPLC) 98.0% – 102.0%
Loss on Drying NMT 0.5%
Residue on Ignition NMT 0.1%
Individual Impurity NMT 0.5%
Water Content NMT 0.5%
Melting Point 150°C – 154°C
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