Dichloromethane, also known as Methylene Chloride, is a volatile chlorinated organic solvent widely used in pharmaceutical manufacturing, chemical processing, extraction, laboratory applications and industrial formulations.
Dichloromethane is a clear, colourless liquid with a characteristic ether-like odour. Its high solvency and relatively low boiling point make it useful for extraction, purification, cleaning and processing applications.
Swapnroop Pharma supplies Dichloromethane in India for pharmaceutical, chemical and industrial applications, subject to the applicable grade and customer specification.
Dichloromethane is a chlorinated hydrocarbon with the molecular formula CH₂Cl₂. It is an effective solvent for a broad range of organic substances and is particularly useful where rapid solvent evaporation is required.
Key characteristics include:
| Property | Value |
|---|---|
| Chemical Name | Dichloromethane |
| Synonym | Methylene Chloride |
| CAS Number | 75-09-2 |
| Molecular Formula | CH₂Cl₂ |
| Molecular Weight | 84.93 g/mol |
| Physical State | Liquid |
| Appearance | Clear, colourless liquid |
| Boiling Point | Approximately 39.6°C |
| Melting Point | Approximately −96.7°C |
| Density | Approximately 1.33 g/cm³ at 20°C |
| Solubility in Water | Slightly soluble |
| Chemical Class | Chlorinated hydrocarbon solvent |
Dichloromethane is used as a processing solvent in certain pharmaceutical and chemical manufacturing operations.
Potential applications include:
Its use in pharmaceutical manufacturing should be controlled according to the applicable process, residual-solvent requirements and regulatory specifications.
In pharmaceutical manufacturing, Dichloromethane may be used as a process solvent during synthesis, extraction or purification.
Where used in an API or pharmaceutical manufacturing process, residual solvent levels in the final material must comply with the applicable regulatory and pharmacopoeial requirements.
Dichloromethane is classified as a Class 2 residual solvent under ICH Q3C because of its toxicological concerns, with a permitted daily exposure of 6.0 mg/day and a concentration limit of 600 ppm under the ICH guideline for pharmaceutical products. The applicable regulatory requirements should always be checked for the specific product and process.
Swapnroop Pharma supplies Dichloromethane for pharmaceutical, chemical and industrial manufacturing applications in India.
Customers can specify the required grade, purity, packaging, quantity and documentation requirements according to the intended application.
As a Dichloromethane supplier in India, Swapnroop Pharma supports pharmaceutical manufacturers, chemical companies, laboratories and industrial users requiring a consistent solvent for approved applications.
Supply requirements may include:
Dichloromethane is commercially produced through industrial chlorination processes and subsequent purification to achieve the required grade.
For pharmaceutical and chemical manufacturing, important quality characteristics include:
Swapnroop Pharma supports bulk Dichloromethane supply in India according to the required grade and customer specification.
Dichloromethane is a volatile hazardous chemical and should be handled and stored in accordance with its current Safety Data Sheet (SDS) and applicable local regulations.
Store in appropriate tightly closed containers in a cool, well-ventilated area away from incompatible materials and sources of excessive heat. Appropriate occupational controls and personal protective equipment should be used during handling.
Dichloromethane requires controlled industrial handling because exposure can present significant health hazards.
Important considerations include:
For pharmaceutical manufacturing, the solvent should be selected and controlled according to the applicable regulatory requirements.
Depending on customer requirements, documentation may include:
Swapnroop Pharma supports customers requiring Dichloromethane for pharmaceutical and chemical manufacturing applications.
Key advantages include:
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |