Corn Starch Pellets are pharmaceutical-grade excipient pellets made primarily from corn starch and are used as functional pellet cores in pharmaceutical formulation development. They can serve as a carrier/core material for coating, layering and multiparticulate formulation processes.
Corn starch is a widely used pharmaceutical excipient with functional roles including filler, binder and disintegrant. Pharmaceutical excipient sources also describe starch-based pellets as suitable cores for enteric-coated and sustained/controlled-release pellet manufacturing.
Unlike API-loaded pellets, Corn Starch Pellets are primarily used as excipient/starter-core material. Their properties such as particle size, moisture, starch content, shape and mechanical characteristics can influence subsequent coating and layering processes.
Corn Starch Pellets can be considered for:
Published product information describes corn starch pellets as pharmaceutical excipient cores used for enteric-coated, sustained-release and controlled-release pellets.
Corn starch is a plant-derived polysaccharide widely used as a pharmaceutical excipient. It can function as a filler, binder and disintegrant in oral solid dosage formulations.
Corn starch can also be combined with other excipients during pelletization. Pharmaceutical literature describes the use of corn starch with microcrystalline cellulose in extrusion-spheronization processes for pellet development.
For finished Corn Starch Pellets, quality characteristics should be established according to the specific product specification. Parameters such as particle-size distribution, moisture, starch content, ash and pH may vary according to grade and manufacturing process.
Corn Starch Pellets can be supplied according to the required particle size, quantity, packaging configuration and applicable product specification. Storage should be in suitable, tightly closed packaging under appropriate dry conditions.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 95.0% – 105.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 0.5% |