Colloidal Silicon Dioxide is a highly dispersed form of amorphous silicon dioxide widely used as a pharmaceutical excipient in solid and semisolid formulations. It is valued primarily for its glidant, anti-caking, adsorbent, thickening, and moisture-control properties.
It is commonly incorporated into tablet and capsule formulations to improve powder flow, reduce interparticle friction, and enhance manufacturing consistency. Depending on its grade and surface characteristics, Colloidal Silicon Dioxide can also be used as an adsorbent and rheology-modifying excipient.
Colloidal Silicon Dioxide consists of finely divided, amorphous silicon dioxide particles with a high specific surface area. Its large surface area enables it to interact effectively with pharmaceutical powders and other formulation ingredients.
It is generally supplied as a white, lightweight, fluffy, amorphous powder and is practically insoluble in water.
Colloidal Silicon Dioxide is used in:
Colloidal Silicon Dioxide provides:
Pharmaceutical-grade Colloidal Silicon Dioxide should comply with the applicable pharmacopoeial and product-specific requirements. Typical quality testing may include:
Exact numerical acceptance criteria should be confirmed against the specific grade specification and applicable USP/NF, Ph. Eur., BP, or IP requirements.
Swapnroop Pharma offers Colloidal Silicon Dioxide for pharmaceutical formulation applications, focusing on consistent quality, grade-specific specifications, batch control, and documentation support.
The material can be supplied for applications involving powder flow improvement, anti-caking, adsorption, moisture control, and formulation stabilization.
Colloidal Silicon Dioxide should be stored in tightly closed packaging in a cool, dry and well-ventilated environment. It should be protected from moisture, contamination, excessive heat, and direct sunlight.
Due to its high surface area and moisture-adsorption capability, proper packaging is particularly important.
Documentation may include:
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |