Climbazole is a specialty cosmetic ingredient mainly used in hair-care and scalp-care formulations, particularly products developed for anti-dandruff applications. It is identified by the INCI name CLIMBAZOLE, CAS Number 38083-17-9, and EC Number 253-775-4. Climbazole is an organic compound used in cosmetic formulations where its functional properties are relevant to scalp and personal-care products. Its use is subject to the intended cosmetic function, product type, and regulatory requirements of the target market. In the European Union, specific provisions distinguish its use as an anti-dandruff ingredient from its use as a preservative.
As a specialty cosmetic ingredient, Climbazole is particularly relevant to manufacturers developing shampoos and other scalp-care formulations. Its technical characteristics, purity, physical form, solubility and compatibility with the formulation should be considered when selecting the raw material.
Climbazole has the chemical name 1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one and the molecular formula C15H17ClN2O2. Its molecular weight is 292.76 g/mol. Commercial technical information describes Climbazole as a white to almost-white powder or crystalline solid. A current TCI specification lists a minimum 98.0 area% by HPLC, a melting range of 96–100°C, and insolubility in water with solubility in methanol. These are supplier reference specifications and should not automatically be treated as the release specification of every manufacturer.
Its defined chemical identity makes Climbazole suitable for controlled use as a specialty personal-care raw material. For procurement, manufacturers should verify the CAS number, grade, analytical method, appearance, purity and batch-specific Certificate of Analysis before production use.
Climbazole is primarily associated with anti-dandruff and scalp-care functionality. Its role in a cosmetic formulation should be considered in relation to the intended product and its overall formulation system. The ingredient can be incorporated into formulations where the product concept requires an anti-dandruff function and where its use is permitted by applicable regulations.
Climbazole is also regulated as a preservative in certain cosmetic applications. Under EU Regulation 2019/698, the permitted preservative concentration is 0.2% in hair lotions, face creams and foot-care products and 0.5% in rinse-off shampoos. Separately, when used as an anti-dandruff ingredient rather than as a preservative, the regulation specifies up to 2% in rinse-off anti-dandruff shampoo under the stated conditions.
These figures are finished-product regulatory limits and should not be confused with the purity or assay specification of the raw material.
Climbazole is particularly relevant to hair-care and scalp-care formulations. Its most recognized application is in rinse-off anti-dandruff shampoos, where it can be incorporated as part of a formulation developed for scalp and hair cleansing. The EU regulatory framework specifically addresses Climbazole for rinse-off anti-dandruff shampoo applications.
It may also be considered in suitable specialty personal-care formulations where its permitted cosmetic function is appropriate. Cosmetic manufacturers can evaluate the ingredient according to the formulation format, intended claims, processing conditions and destination-market requirements.
For commercial development, the finished formulation should be assessed as a whole rather than relying only on the function of an individual raw material. The final product's formulation, stability, compatibility and regulatory status all influence how Climbazole can be used.
Climbazole's physical properties should be considered during formulation development. Published commercial data identify it as insoluble in water and soluble in methanol, which means that the method of incorporation, dispersion or solubilization needs to be selected according to the formulation system.
Formulators should evaluate compatibility with surfactants, conditioners, emulsifiers, fragrances and other functional ingredients. Processing parameters such as order of addition, temperature and mixing conditions should be established through formulation trials using the actual grade supplied.
The intended concentration should also be determined according to the cosmetic function and applicable regulations. In particular, anti-dandruff use and preservative use can have different regulatory concentration limits. This distinction is important for manufacturers preparing products for international markets.
Quality control should be based on an approved specification and validated analytical method. Where HPLC is the agreed method, the assay requirement should correspond to the actual product specification rather than being copied from an unrelated supplier.
A Climbazole cosmetic ingredient manufacturer in India should provide a clearly identified material supported by appropriate technical specifications and batch documentation. Cosmetic and personal-care manufacturers looking for a Climbazole cosmetic ingredient supplier in India should evaluate factors such as chemical identity, purity, appearance, analytical method, packaging, Certificate of Analysis, Safety Data Sheet and batch traceability.
For Climbazole manufacturing in India, consistent quality characteristics are important for businesses using the ingredient in commercial hair-care and scalp-care formulations. Bulk buyers may also require defined packaging, quantities and technical documentation according to their production and procurement requirements.
Companies sourcing Climbazole bulk cosmetic ingredient in India can evaluate the material according to their formulation requirements, quality standards and intended destination market. A reliable supplier relationship should be based on documented specifications and batch-specific quality information rather than product naming alone.
Swapnroop provides a B2B-oriented approach to Climbazole cosmetic ingredient supply, with focus on product-specific technical information and requirements relevant to cosmetic and personal-care manufacturers. Buyers can evaluate Climbazole according to its intended application, required specifications, documentation and bulk procurement needs.
The ingredient can be considered for manufacturers looking for a Climbazole cosmetic ingredient manufacturer and supplier in India, particularly for hair-care, scalp-care and anti-dandruff formulation development. Technical characteristics such as identity, purity, physical form, solubility and application suitability can be considered when establishing the appropriate specification for commercial use.
| Parameter | Specification |
|---|---|
| Appearance | White or colourless crystals / white powder |