Citalopram Hydrochloride is the hydrochloride salt of citalopram, a selective serotonin reuptake inhibitor (SSRI). Citalopram increases serotonergic activity in the central nervous system by inhibiting the reuptake of serotonin.
Citalopram is used therapeutically as an antidepressant and is associated primarily with the treatment of major depressive disorder.
| Parameter | Details |
|---|---|
| Product Name | Citalopram Hydrochloride |
| Generic Name | Citalopram |
| Salt Form | Hydrochloride |
| Category | Active Pharmaceutical Ingredient |
| Therapeutic Class | Antidepressant |
| Pharmacological Class | Selective Serotonin Reuptake Inhibitor (SSRI) |
| Physical Form | Solid |
| Appearance | White to off-white powder |
| Molecular Formula | C₂₀H₂₂BrFN₂O (for the approved hydrobromide API) |
| Molecular Weight | 405.30 g/mol (for citalopram hydrobromide) |
Citalopram is a selective serotonin reuptake inhibitor used primarily for the treatment of major depressive disorder.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% on dried basis |
| Loss on Drying | NMT 0.1% |
| pH (1% Solution) | 2.0 – 4.0 |
| Individual Impurity | ≤ 0.5% |
| Melting Point | 150°C – 154°C |