Cinoxacin is a synthetic antibacterial active pharmaceutical ingredient belonging to the quinolone/cinnoline-related class of antimicrobial compounds. It has antibacterial activity primarily against susceptible Gram-negative bacteria and was historically used for the treatment of urinary tract infections.
Cinoxacin is chemically identified as 1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid. It has the molecular formula C₁₂H₁₀N₂O₅ and molecular weight 262.22 g/mol.
| Parameter | Details |
|---|---|
| Product Name | Cinoxacin |
| Generic Name | Cinoxacin |
| CAS Number | 28657-80-9 |
| Molecular Formula | C₁₂H₁₀N₂O₅ |
| Molecular Weight | 262.22 g/mol |
| Chemical Class | Cinnoline / quinolone-related antibacterial |
| Therapeutic Class | Synthetic antibacterial |
| Physical Form | Solid / powder or crystals |
| Stereochemistry | Achiral |
| UNII | LMK22VUH23 |
The CAS number, formula, molecular weight and achiral character are supported by PubChem and FDA/NCATS substance records.
Cinoxacin was historically used as an oral antibacterial for urinary tract infections. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV.
| Parameter | Specification |
|---|---|
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Heavy Metals | NMT 10 ppm |
| Total Impurities | ≤ 1.5% |
| Water Content | NMT 1.0% |
| Melting Point | 150°C – 154°C |