Carvedilol Phosphate SR Pellets are pharmaceutical-grade sustained-release multiparticulate pellets containing Carvedilol Phosphate. Carvedilol Phosphate is a phosphate salt form of Carvedilol. The commercially identified phosphate hemihydrate has CAS Number 610309-89-2, molecular formula C₄₈H₆₀N₄O₁₇P₂, and molecular weight approximately 1027.0 g/mol.
The sustained-release pellet system is designed to regulate the release of Carvedilol over an extended period. The release profile can be controlled through appropriate matrix or functional coating technology, with the final formulation depending on active loading, pellet size, coating characteristics and dissolution requirements.
Commercial pharmaceutical pellet portfolios specifically document Carvedilol Phosphate SR Pellets at 7% and 20% w/w. Another commercial specification lists 20% w/w Carvedilol Phosphate SR Pellets.
For the SDP website, the exact available strength should be published only when it matches the current SDP product specification or COA.
Carvedilol Phosphate SR Pellets are designed for oral formulations requiring an extended and controlled release profile.
The multiparticulate pellet format is suitable for incorporation into capsule dosage forms according to the selected strength and formulation requirements.
The pellets provide a flexible platform for development of sustained-release oral formulations where release rate and dissolution characteristics are controlled.
Individual pellets can provide a multiparticulate approach for distributing the active ingredient across multiple coated or matrix-controlled units.
Carvedilol Phosphate SR Pellets can be supplied in bulk according to active loading, pellet-size distribution and approved quality specifications.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 0.5% |
| Residue on Ignition | NMT 0.1% |
| Water Content | NMT 0.5% |