Carbomer 974G is a carbomer-based polymeric excipient used for viscosity modification, thickening, rheology control and suspension stabilization in formulation systems. Carbomers are crosslinked polymers of acrylic acid that can develop viscosity when dispersed in water and appropriately neutralized.
Carbomer 974G is positioned as a functional excipient rather than an active pharmaceutical ingredient. Its polymeric structure allows it to modify the physical and flow characteristics of formulations at relatively low concentrations.
Carbomer excipients are synthetic, high-molecular-weight crosslinked acrylic acid polymers supplied in powder or granular forms depending on the specific grade. They are widely used where controlled viscosity, thickening, suspension and rheological properties are required.
The performance of a carbomer depends on its polymer structure, degree of crosslinking, concentration, neutralization, pH, ionic environment and processing conditions. Therefore, the exact performance characteristics of Carbomer 974G should be evaluated according to its specific product specification and technical documentation.
Carbomer excipients can be used in pharmaceutical formulation development as viscosity modifiers, thickening agents, suspending agents and rheology modifiers.
Depending on the specific grade and formulation, carbomer polymers may be used in topical preparations, gels, creams, suspensions and other pharmaceutical dosage forms where rheological control is required.
Carbomer polymers can also support formulation stability by helping maintain the distribution of suspended ingredients and providing controlled flow characteristics.
Carbomer 974G can provide viscosity development after suitable dispersion and neutralization. Its rheological behavior can be influenced by concentration, pH, neutralizing agent, electrolytes and other formulation ingredients.
The polymeric nature of carbomer allows formulation developers to achieve viscosity and flow modification using relatively low concentrations. The exact concentration and processing conditions should be established through formulation development and validated according to the intended application.
Carbomer materials are crosslinked polyacrylic acid polymers. They are classified as functional pharmaceutical excipients and are not APIs.
Carbomer nomenclature and specifications can vary between manufacturers and grades. Therefore, the exact compendial designation, CAS identification, viscosity specification and regulatory status of Carbomer 974G should be confirmed against the supplied manufacturer's technical documentation.
Quality control for Carbomer 974G may include identification, viscosity, loss on drying, carboxylic acid content, pH of a specified dispersion, residual solvents, residue on ignition or sulfated ash, and other applicable product-specific tests.
The acceptance criteria should always be taken from the approved specification and Certificate of Analysis for the actual Carbomer 974G grade supplied.
Swapnroop offers pharmaceutical excipient products for pharmaceutical formulation and manufacturing applications. Carbomer 974G can be positioned for customers seeking carbomer-based excipients for viscosity modification, thickening, suspension stabilization and rheology-control applications.
The available grade, specification, documentation, packaging and applicable pharmacopeial compliance should be confirmed according to the specific material supplied.
Carbomer 974G should be maintained in its original, tightly closed packaging and protected from moisture and contamination. Storage conditions should follow the manufacturer's approved technical documentation.
The recommended storage temperature, shelf life and handling requirements should be taken from the product-specific specification or Certificate of Analysis.
Depending on the supplied grade and customer requirements, documentation may include a Certificate of Analysis, Safety Data Sheet, Technical Data Sheet, product specification and applicable quality or regulatory documentation.
Carbomer 974G is a functional polymeric excipient intended for applications requiring viscosity modification, thickening, suspension stabilization and rheological control. Its use allows pharmaceutical formulators to modify formulation properties according to the requirements of the dosage form and manufacturing process.
Customers should confirm the exact grade, specification, compliance status and documentation before selecting Carbomer 974G for a particular pharmaceutical formulation.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Loss on Drying | NMT 2.0% |
| Residue on Ignition | NMT 2.5% |
| Heavy Metals | NMT 20 ppm |
| pH (1% Solution) | 2.5 – 3.0 |
| Individual Impurity | NMT 0.5% |
| Total Impurities | ≤ 1.5% |
| Water Content | NMT 2.0% |