Carbomer 974 NF is a high-molecular-weight, crosslinked polyacrylic acid polymer used as a functional pharmaceutical excipient for viscosity modification, suspension stabilization, bioadhesion and controlled-release formulations. For pharmaceutical-grade applications, Carbomer 974P NF is classified as Carbomer Homopolymer Type B under USP/NF.
Carbomer 974P NF is supplied as a white, fluffy powder and is manufactured using ethyl acetate, a Class 3 solvent. It provides high viscosity and strong suspending properties, making it suitable for a variety of oral, topical and bioadhesive pharmaceutical formulations.
Carbomer 974 NF is a pharmaceutical excipient belonging to the carbomer family of high-molecular-weight crosslinked polyacrylic acid polymers. It is primarily used to modify rheology and viscosity and to improve suspension stability and formulation performance.
The pharmaceutical-grade Carbomer 974P NF has a viscosity specification of 29,400–39,400 cP at 25°C under the manufacturer's specified test conditions.
Carbomer 974P NF is a Carbomer Homopolymer Type B. The polymer consists of acrylic acid crosslinked with a polyfunctional crosslinking agent and is designed to hydrate and swell in suitable aqueous systems.
After neutralization, the polymer develops significant viscosity and rheological properties. This makes it useful in formulations requiring controlled flow, suspension stabilization, gel formation, bioadhesion and modified drug release.
Carbomer 974 NF / 974P NF can be used in:
Lubrizol specifically identifies 974P NF for suspensions, bioadhesive formulations, roller compaction and solid dosage applications, as well as topical pharmaceutical applications.
Carbomer 974P NF is particularly useful where a formulation requires high viscosity and suspension performance. Its high-viscosity profile supports pharmaceutical applications involving oral suspensions, bioadhesive systems and modified-release solid dosage formulations.
Pharmaceutical-grade Carbomer 974P NF is evaluated through identification testing, carboxylic acid content, viscosity, loss on drying, residual solvent, residual monomer and sulphated ash testing.
The published specification includes:
These are the published specifications for Carbopol® 974P NF polymer and should not be presented as universal specifications for every commercially available carbomer 974 product.
Swapnroop provides pharmaceutical excipient product information and sourcing support for Carbomer 974 NF / Carbomer 974P NF for pharmaceutical formulation and manufacturing applications.
The product is suitable for customers seeking a pharmaceutical-grade carbomer for oral suspensions, controlled-release formulations, bioadhesive systems, rheology modification and other pharmaceutical applications.
Applicable grade, specification, regulatory status, documentation and batch-specific quality requirements should be confirmed before commercial use.
Carbomer 974 NF should be stored in tightly closed packaging and protected from excessive moisture, contamination and unsuitable environmental conditions.
Packaging configurations can be selected according to laboratory, formulation-development, commercial manufacturing and bulk pharmaceutical requirements.
Depending on the applicable product and supply arrangement, documentation may include:
Carbomer 974 NF / 974P NF offers high viscosity, suspension stabilization, rheology modification and bioadhesive functionality in pharmaceutical formulation systems.
Its established use in oral suspensions, bioadhesive formulations and solid dosage applications makes it a valuable pharmaceutical excipient for formulation development and manufacturing.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 2.0% |
| Residue on Ignition | NMT 2.5% |
| Water Content | NMT 2.0% |