Pharmaceutical-Grade Carbidopa IR Pellets for Immediate-Release Oral Formulations
Carbidopa IR Pellets are multiparticulate pharmaceutical formulations designed for immediate-release oral dosage applications. Carbidopa is identified by CAS Number 28860-95-9, with molecular formula C₁₀H₁₄N₂O₄ and molecular weight 226.23 g/mol for the anhydrous form. Carbidopa is also commercially encountered as the monohydrate, which has CAS Number 38821-49-7 and molecular weight 244.24 g/mol.
The SDP pellet product list specifies Carbidopa IR Pellets at 12.50% strength. This provides a defined active-loading option for pharmaceutical manufacturers developing immediate-release multiparticulate formulations.
The IR pellet format is designed to provide an immediate-release profile from the multiparticulate system. Finished-pellet performance depends on the formulation composition, active loading, pellet characteristics and applicable release specification.
Carbidopa is a chiral pharmaceutical ingredient. The anhydrous form has the molecular formula C₁₀H₁₄N₂O₄ and molecular weight 226.23 g/mol. The monohydrate form has the formula C₁₀H₁₆N₂O₅ and molecular weight 244.24 g/mol.
For Carbidopa IR Pellets, the active ingredient is incorporated into a multiparticulate pellet system intended for immediate-release formulation applications. The 12.50% value represents the pellet active loading and should not be confused with the purity specification of the Carbidopa raw material.
Carbidopa IR Pellets — 12.50%
The 12.50% strength is listed in the SDP pellet product catalogue.
Carbidopa IR Pellets can be considered for:
Carbidopa IR Pellets can be supplied in suitable bulk packaging according to customer requirements. Strength, batch quantity, packaging configuration and applicable documentation can be specified according to the intended pharmaceutical formulation.
| Parameter | Specification |
|---|---|
| Appearance | white to off-white crystalline powder |
| Identification | IR & HPLC compliant |
| Assay (HPLC) | 98.0% – 102.0% |
| Loss on Drying | NMT 1.0% |
| Residue on Ignition | NMT 0.5% |
| Individual Impurity | NMT 0.5% |
| Total Impurities | NMT 1.0% |
| Water Content | NMT 1.0% |